中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2015年
6期
598-602
,共5页
李昱%周航%牟笛%殷文武%余宏杰
李昱%週航%牟笛%慇文武%餘宏傑
리욱%주항%모적%은문무%여굉걸
发热伴血小板减少综合征%监测%流行病学
髮熱伴血小闆減少綜閤徵%鑑測%流行病學
발열반혈소판감소종합정%감측%류행병학
Severe fever with thrombocytopenia syndrome%Surveillance%Epidemiology
目的 分析中国2011-2014年发热伴血小板减少综合征(SFTS)流行病学特征及其监测情况.方法 利用疾病监测信息管理系统的法定传染病报告数据分析SFTS三间分布和病例审核的及时性,收集突发公共卫生事件信息管理系统聚集性疫情资料分析其聚集性,采用 Cochran-Armitage趋势检验其随年龄变化的病死率,利用x2检验不同组别的病死率差异,检验水准取α=0.05.结果 2011-2014年23个省份共报告5 352例SFTS,其中16个省报告实验室诊断病例2 750例,占报告病例总数的51.4％,病死率约为7.9％,病例主要分布在河南、山东、湖北、安徽、辽宁、浙江、江苏7省,占全国病例总数的99.3％.4-10月为该病流行季,5-7月为疫情高峰.病例职业主要为农民(88.3％).发病年龄主要集中在50～74岁,占病例总数的67.6％.病死率由40～44岁年龄组的3.7％逐步增加到≥80岁年龄组的13.5％.曾被误诊的病例其病死率高于其他病例(x2=12.726,P＜0.001),0R=3.06(95％CI:1.61～ 5.90).聚集性疫情续发病例最可能的暴露因素是接触病例血液.结论 SFTS报告发病数呈逐年上升趋势.河南、湖北和安徽交界地区以及山东、辽宁发病例数较多,病例呈高度散发状态,5-7月为疫情高峰季,农民和中老年人是发病高危人群;偶有聚集性暴发疫情,且与接触病例或尸体血液相关;病例高龄和误诊是死亡的危险因素.
目的 分析中國2011-2014年髮熱伴血小闆減少綜閤徵(SFTS)流行病學特徵及其鑑測情況.方法 利用疾病鑑測信息管理繫統的法定傳染病報告數據分析SFTS三間分佈和病例審覈的及時性,收集突髮公共衛生事件信息管理繫統聚集性疫情資料分析其聚集性,採用 Cochran-Armitage趨勢檢驗其隨年齡變化的病死率,利用x2檢驗不同組彆的病死率差異,檢驗水準取α=0.05.結果 2011-2014年23箇省份共報告5 352例SFTS,其中16箇省報告實驗室診斷病例2 750例,佔報告病例總數的51.4％,病死率約為7.9％,病例主要分佈在河南、山東、湖北、安徽、遼寧、浙江、江囌7省,佔全國病例總數的99.3％.4-10月為該病流行季,5-7月為疫情高峰.病例職業主要為農民(88.3％).髮病年齡主要集中在50～74歲,佔病例總數的67.6％.病死率由40～44歲年齡組的3.7％逐步增加到≥80歲年齡組的13.5％.曾被誤診的病例其病死率高于其他病例(x2=12.726,P＜0.001),0R=3.06(95％CI:1.61～ 5.90).聚集性疫情續髮病例最可能的暴露因素是接觸病例血液.結論 SFTS報告髮病數呈逐年上升趨勢.河南、湖北和安徽交界地區以及山東、遼寧髮病例數較多,病例呈高度散髮狀態,5-7月為疫情高峰季,農民和中老年人是髮病高危人群;偶有聚集性暴髮疫情,且與接觸病例或尸體血液相關;病例高齡和誤診是死亡的危險因素.
목적 분석중국2011-2014년발열반혈소판감소종합정(SFTS)류행병학특정급기감측정황.방법 이용질병감측신식관리계통적법정전염병보고수거분석SFTS삼간분포화병례심핵적급시성,수집돌발공공위생사건신식관리계통취집성역정자료분석기취집성,채용 Cochran-Armitage추세검험기수년령변화적병사솔,이용x2검험불동조별적병사솔차이,검험수준취α=0.05.결과 2011-2014년23개성빈공보고5 352례SFTS,기중16개성보고실험실진단병례2 750례,점보고병례총수적51.4％,병사솔약위7.9％,병례주요분포재하남、산동、호북、안휘、료녕、절강、강소7성,점전국병례총수적99.3％.4-10월위해병류행계,5-7월위역정고봉.병례직업주요위농민(88.3％).발병년령주요집중재50～74세,점병례총수적67.6％.병사솔유40～44세년령조적3.7％축보증가도≥80세년령조적13.5％.증피오진적병례기병사솔고우기타병례(x2=12.726,P＜0.001),0R=3.06(95％CI:1.61～ 5.90).취집성역정속발병례최가능적폭로인소시접촉병례혈액.결론 SFTS보고발병수정축년상승추세.하남、호북화안휘교계지구이급산동、료녕발병례수교다,병례정고도산발상태,5-7월위역정고봉계,농민화중노년인시발병고위인군;우유취집성폭발역정,차여접촉병례혹시체혈액상관;병례고령화오진시사망적위험인소.
Objective To analyze the epidemiological features and surveillance management programs on severe fever with thrombocytopenia syndrome (SFTS) in China from 2011 to 2014.Methods The analysis of epidemiological characteristics and surveillance management programs was based on the annual reporting data collected from the National Disease Reporting Information System while the description of cluster incidents was based on those reports collected from the Public Health Emergency Information Management System (PHEIMS).Association between age groups and fatality rate was tested under the Cochran-Armitage Trend Test.The difference of fatality rates between differing groups was analyzed,using the chi-square test,with statistical significance on α=0.05.Results Between 2011 and 2014,5 352 suspected,probable and lab-confirmed cases of SFTS were reported in 23 provinces,of which 16 provinces reported 2 750 lab-confirmed cases with a fatality of 7.9％,accounting for 51.4％ of all the cases,nation-wide.Henan,Shandong,Hubei,Anhui,Liaoning,Zhejiang and Jiangsu reported 99.3％ of those lab-confirmed cases.The period between April and October appeared the epidemic season,with its peak from May to July.Most cases were farmers,accounted for 88.3％ of the lab-confirmed cases.People at the age between 50-74 occupied 67.6％ of all the cases.Fatality of the disease continually increased from 3.7％ in the age group 40-44 to 13.5％ in the age group older than 80.Fatality rates appeared statistically different between the groups with or without misdiagnosis,with OR as 3.06 (95％CI:1.61-5.90).Secondary cases of the cluster incidents were most likely to result from contacting the blood of the index cases.Conclusion Number of reported SFTS cases showed a rising trend in China.Henan,Hubei,Anhui,Shandong and Liaoning provinces appeared at high risk of the disease.Geographical distribution of the SFTS cases' seemed highly sporadic,with May to July being the peak season.Farmers and elderly were considered as high risk population.Occasionally,cluster incidents might be seen,as the result of contacting the blood of cases or corpses.Being at older age and misdiagnosis seemed to be risk factors for fatality.
