临床医学
臨床醫學
림상의학
CLINICAL MEDICINE
2015年
6期
16-17
,共2页
急性心肌梗死%室性心律失常%胺碘酮%美托洛尔
急性心肌梗死%室性心律失常%胺碘酮%美託洛爾
급성심기경사%실성심률실상%알전동%미탁락이
Acute myocardial infarction%Ventricular arrhythmia%Amiodarone%Metoprolol
目的：观察胺碘酮联合小剂量美托洛尔治疗急性心肌梗死（AMI）并室性心律失常的临床疗效。方法选取入院治疗的 AMI 并室性心律失常患者76例为研究对象，采用抽签法将患者分为两组，对照组采用胺碘酮治疗，观察组在对照组的基础上辅以小剂量美托洛尔，观察两组患者的临床疗效，记录治疗后左心室舒张末容量（LVEDV）、心率（HR）、左室射血分数（LVEF）。结果观察组治疗有效率为84.21%，高于对照组（63.16%）；观察组室性心律失常治疗有效率为92.11%，高于对照组（63.86%），差异有统计学意义（P ﹤0.05）。观察组治疗后 HR、LVEDV 分别为（67.26±21.08）次/ min、（128.67±22.58）ml，均低于对照组；LVEF 为（42.36±5.54）ml，高于对照组，差异有统计学意义（P ﹤0.05）。结论在胺碘酮治疗 AMI 并室性心律失常的基础上辅以小剂量美托洛尔能够提高临床疗效，改善患者的心功能。
目的：觀察胺碘酮聯閤小劑量美託洛爾治療急性心肌梗死（AMI）併室性心律失常的臨床療效。方法選取入院治療的 AMI 併室性心律失常患者76例為研究對象，採用抽籤法將患者分為兩組，對照組採用胺碘酮治療，觀察組在對照組的基礎上輔以小劑量美託洛爾，觀察兩組患者的臨床療效，記錄治療後左心室舒張末容量（LVEDV）、心率（HR）、左室射血分數（LVEF）。結果觀察組治療有效率為84.21%，高于對照組（63.16%）；觀察組室性心律失常治療有效率為92.11%，高于對照組（63.86%），差異有統計學意義（P ﹤0.05）。觀察組治療後 HR、LVEDV 分彆為（67.26±21.08）次/ min、（128.67±22.58）ml，均低于對照組；LVEF 為（42.36±5.54）ml，高于對照組，差異有統計學意義（P ﹤0.05）。結論在胺碘酮治療 AMI 併室性心律失常的基礎上輔以小劑量美託洛爾能夠提高臨床療效，改善患者的心功能。
목적：관찰알전동연합소제량미탁락이치료급성심기경사（AMI）병실성심률실상적림상료효。방법선취입원치료적 AMI 병실성심률실상환자76례위연구대상，채용추첨법장환자분위량조，대조조채용알전동치료，관찰조재대조조적기출상보이소제량미탁락이，관찰량조환자적림상료효，기록치료후좌심실서장말용량（LVEDV）、심솔（HR）、좌실사혈분수（LVEF）。결과관찰조치료유효솔위84.21%，고우대조조（63.16%）；관찰조실성심률실상치료유효솔위92.11%，고우대조조（63.86%），차이유통계학의의（P ﹤0.05）。관찰조치료후 HR、LVEDV 분별위（67.26±21.08）차/ min、（128.67±22.58）ml，균저우대조조；LVEF 위（42.36±5.54）ml，고우대조조，차이유통계학의의（P ﹤0.05）。결론재알전동치료 AMI 병실성심률실상적기출상보이소제량미탁락이능구제고림상료효，개선환자적심공능。
Objective To observe the clinical efficacy of amiodarone combined with small dose of metoprolol on acute myo-cardial infarction(AMI)and ventricular arrhythmia. Methods Seventy-six patients with AMI and ventricular arrhythmias were selected as research objects and divided into two groups,the patients in control group were given amiodarone treatment,and the patients in the observation group were given small dose of metoprolol in addition. The clinical effects of two groups of patients were observed and HR,LVEF,LVEDV value after treatment was recorded. Results The effective rate of treatment group (84. 21% )was higher than that of the control group(63. 16% ). The effective rate of treatment group for ventricular arrhythmia was 92. 11% and was 63. 86% in control group,there was significant difference(P ﹤ 0. 05). The observation group after treat-ment,HR,LVEDV were(67. 26 ± 21. 08)beat/ min and(128. 67 ± 22. 58)ml,which was lower than that of control group, LVEF[(42. 36 ± 5. 54 ) ml ] was higher than that of control group,there were significant differences( P ﹤ 0. 05 ). Conclusion On the basis of amiodarone in the treatment of AMI and ventricular arrhythmia,small dose of metoprolol can im-prove the clinical efficacy and improve heart function of patients.
