中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2015年
5期
517-522
,共6页
杨凯博%胡悦东%刘磊%吴京阳%张劲松%卢迪%陈蕾
楊凱博%鬍悅東%劉磊%吳京暘%張勁鬆%盧迪%陳蕾
양개박%호열동%류뢰%오경양%장경송%로적%진뢰
糖尿病性视网膜病变%糖尿病性黄斑水肿%眼轴长度%屈光不正
糖尿病性視網膜病變%糖尿病性黃斑水腫%眼軸長度%屈光不正
당뇨병성시망막병변%당뇨병성황반수종%안축장도%굴광불정
Axial length%Diabetic retinopathy%Diabetic macular edema%Refractive error
目的 研究眼轴长度与糖尿病性视网膜病变(diabetic retinopathy, DR)及糖尿病性黄斑水肿(diabetic macular edema,DME)的相关性.方法 临床病例系列研究.收集2013年10月至2014年10月于中国医科大学附属第一医院糖尿病眼病防治中心就诊的2型糖尿病患者327例,应用A型超声测量眼轴长度,自动电脑验光仪测量屈光度,散瞳眼底照相进行DR和DME的分级:无DR、轻度NPDR、中度NPDR、重度NPDR和PDR,以及无DME、轻度DME、中度DME和重度DME,光学相干断层扫描(optical coherence tomography, OCT)确诊糖尿病性黄斑水肿.结果 经过多元回归分析后,眼轴越长越不容易患重度NPDR,差异有统计学意义(OR,0.50; 95％CI,0.37～0.98;P=0.04)和PDR (OR,0.63;95％CI,0.26～0.98;P=0.04).眼轴越长更不容易患轻度DME,差异有统计学意义(OR,0.61;95％CI,0.37～0.97;P=0.02),中度DME (OR,0.61;95％ CI,0.37～0.99;P =0.03)和重度DME (OR,0.50;95％CI,0.37～0.96;P=0.03).结论 眼轴长度与DR和DME之间存在相关性,长眼轴是重度DR和DME的保护性因素.
目的 研究眼軸長度與糖尿病性視網膜病變(diabetic retinopathy, DR)及糖尿病性黃斑水腫(diabetic macular edema,DME)的相關性.方法 臨床病例繫列研究.收集2013年10月至2014年10月于中國醫科大學附屬第一醫院糖尿病眼病防治中心就診的2型糖尿病患者327例,應用A型超聲測量眼軸長度,自動電腦驗光儀測量屈光度,散瞳眼底照相進行DR和DME的分級:無DR、輕度NPDR、中度NPDR、重度NPDR和PDR,以及無DME、輕度DME、中度DME和重度DME,光學相榦斷層掃描(optical coherence tomography, OCT)確診糖尿病性黃斑水腫.結果 經過多元迴歸分析後,眼軸越長越不容易患重度NPDR,差異有統計學意義(OR,0.50; 95％CI,0.37～0.98;P=0.04)和PDR (OR,0.63;95％CI,0.26～0.98;P=0.04).眼軸越長更不容易患輕度DME,差異有統計學意義(OR,0.61;95％CI,0.37～0.97;P=0.02),中度DME (OR,0.61;95％ CI,0.37～0.99;P =0.03)和重度DME (OR,0.50;95％CI,0.37～0.96;P=0.03).結論 眼軸長度與DR和DME之間存在相關性,長眼軸是重度DR和DME的保護性因素.
목적 연구안축장도여당뇨병성시망막병변(diabetic retinopathy, DR)급당뇨병성황반수종(diabetic macular edema,DME)적상관성.방법 림상병례계렬연구.수집2013년10월지2014년10월우중국의과대학부속제일의원당뇨병안병방치중심취진적2형당뇨병환자327례,응용A형초성측량안축장도,자동전뇌험광의측량굴광도,산동안저조상진행DR화DME적분급:무DR、경도NPDR、중도NPDR、중도NPDR화PDR,이급무DME、경도DME、중도DME화중도DME,광학상간단층소묘(optical coherence tomography, OCT)학진당뇨병성황반수종.결과 경과다원회귀분석후,안축월장월불용역환중도NPDR,차이유통계학의의(OR,0.50; 95％CI,0.37～0.98;P=0.04)화PDR (OR,0.63;95％CI,0.26～0.98;P=0.04).안축월장경불용역환경도DME,차이유통계학의의(OR,0.61;95％CI,0.37～0.97;P=0.02),중도DME (OR,0.61;95％ CI,0.37～0.99;P =0.03)화중도DME (OR,0.50;95％CI,0.37～0.96;P=0.03).결론 안축장도여DR화DME지간존재상관성,장안축시중도DR화DME적보호성인소.
Objective To evaluate the association of axial length with diabetic retinopathy (DR) and diabetic macular edema (DME) in persons with type-2 diabetes.Methods A total of 327 participants suffering from type-2 diabetes were chosen in Liaoning Diabetes Eye Center from October 2013 to October 2014,axial length was measured by A-scan ultrasound,refractive error was measured using automatic refractometry,the severity of DR was graded into non-DR,mild NPDR,moderate NPDR,severe NPDR and PDR and DME,severity was classified as no DME,mild DME,moderate DME and severe DME according mydriatic fundus photographs,DME was confirmed by optical coherence tomography.Results In multivariate regression models,eyes with longer axial length were less likely to have severe NPDR (OR,0.50; 95％CI,0.37-0.98; P =0.04) and PDR (OR,0.63; 95％CI,0.26-0.98; P =0.04) and had a lower risk of mild DME (OR,0.61; 95％CI,0.37-0.97; P =0.02),moderate DME (OR,0.61; 95％CI,0.37-0.99; P =0.03) and severe DME (OR,0.50; 95％ CI,0.37-0.96,P =0.03).Conclusions Axial length is associated with the presence and severity of DR and DME.Longer axial length is protective of severe DR and any DME.
