CAJ | 학술논문

目的：探讨四维CT的放疗技术在肺癌三维调强放射治疗中的应用效果。方法回顾性分析我院42例肺癌患者应用四维CT的放疗技术治疗的临床资料。结果42例患者均获得随访，其中完全缓解6例，部分缓解27例，无好转8例，进展1例，总有效率为78．57％。其中急性放射性肺损伤1级34例（80．95％），2级7例（16．67％），3级1例（2．38％），急性放射性食管炎1级34例（80．95％），2级3例（7．14％）。4D计划CTV高于3D计划，PTV小于3D计划，肺V20、MLD低于3D计划，差异有统计学意义（ P＜0．05）。结论四维CT应用于肺癌三维调强放射治疗中可行、有效，能够减少计划靶区的体积，提高放射治疗疗效。
목적：탐토사유CT적방료기술재폐암삼유조강방사치료중적응용효과。방법회고성분석아원42례폐암환자응용사유CT적방료기술치료적림상자료。결과42례환자균획득수방，기중완전완해6례，부분완해27례，무호전8례，진전1례，총유효솔위78．57％。기중급성방사성폐손상1급34례（80．95％），2급7례（16．67％），3급1례（2．38％），급성방사성식관염1급34례（80．95％），2급3례（7．14％）。4D계화CTV고우3D계화，PTV소우3D계화，폐V20、MLD저우3D계화，차이유통계학의의（ P＜0．05）。결론사유CT응용우폐암삼유조강방사치료중가행、유효，능구감소계화파구적체적，제고방사치료료효。
Objective:To investigate the efficacy of four-dimensional CT for the three-dimensional intensity modulated radiotherapy of patients with lung cancer.Methods A retrospective analysis of clinical data of 38 cases of lung cancer patients in the four-dimen-sional CT radiotherapy treatment.Results The total efficiency was 78.57%,the displacement of lung tumor respiratory motion was differ-ent in three dimensions, especially in the Vertical direction about(9.0 ±2.2) mm, Accuracy of the distance was2.5mm,the plan-4Ds CTV was bigger than Plan-3D,but its PTV was less than the Plan-3D significantly, at the same time its lung V20,MLD were both less than the Plan-3D,and the difference was statistically significant(P<0.05).Conclusion Through applications to four-dimensional CT is feasible, effective, and can reduce the volume of the planning target volume, and help to improve the accuracy of radiotherapy.