黑龙江医学
黑龍江醫學
흑룡강의학
HEILONGJIANG MEDICAL JOURNAL
2015年
5期
502-504
,共3页
超声电导%穴位%升白贴%化疗%骨髓抑制%消化道反应
超聲電導%穴位%升白貼%化療%骨髓抑製%消化道反應
초성전도%혈위%승백첩%화료%골수억제%소화도반응
Electrophonophoresis%Acupoint%Chemotherapy%Shenbai Patch%Marrow depression%Gastrointestinal reactions
目的：观察穴位超声电导升白贴剂对化疗引起骨髓抑制的预防作用。方法将90例接受常规化疗的肿瘤患者随机分为治疗组（A组）、对照组（B组）和空白组（C组），每组各30例。 A、B两组在化疗前5 d开始进行足三里和血海穴的穴位超声电导治疗，A组使用升白贴片；B组使用空白贴片，连续7 d；C组不接受其他干预。观察化疗后骨髓抑制发生率及消化道反应等情况。结果三组总体骨髓抑制发生率有显著性差异，A组最低（A组40．0％、B组66．7％、C组70．0％，P＝0．035）；A组、B组总体恶心发生率均低于C组（分别为33．3％、36．7％、60．0％），在严重恶心发生率方面达到了显著性差异（ A组10．0％、B组13．3％、C组33．3％，P＝0．044）；同样，A组和B组的总体呕吐发生率亦低于C组（A组26．7％、B组30．0％、C组56．7％，P＝0．032）。 A、B组未见局部皮肤出现皮疹、过敏等不良反应。结论穴位超声电导升白贴可以有效预防化疗引起的骨髓抑制，主要减少轻度骨髓抑制的发生率。此外，穴位超声电导能减轻化疗导致的消化道反应，该治疗方法安全、有效。
目的：觀察穴位超聲電導升白貼劑對化療引起骨髓抑製的預防作用。方法將90例接受常規化療的腫瘤患者隨機分為治療組（A組）、對照組（B組）和空白組（C組），每組各30例。 A、B兩組在化療前5 d開始進行足三裏和血海穴的穴位超聲電導治療，A組使用升白貼片；B組使用空白貼片，連續7 d；C組不接受其他榦預。觀察化療後骨髓抑製髮生率及消化道反應等情況。結果三組總體骨髓抑製髮生率有顯著性差異，A組最低（A組40．0％、B組66．7％、C組70．0％，P＝0．035）；A組、B組總體噁心髮生率均低于C組（分彆為33．3％、36．7％、60．0％），在嚴重噁心髮生率方麵達到瞭顯著性差異（ A組10．0％、B組13．3％、C組33．3％，P＝0．044）；同樣，A組和B組的總體嘔吐髮生率亦低于C組（A組26．7％、B組30．0％、C組56．7％，P＝0．032）。 A、B組未見跼部皮膚齣現皮疹、過敏等不良反應。結論穴位超聲電導升白貼可以有效預防化療引起的骨髓抑製，主要減少輕度骨髓抑製的髮生率。此外，穴位超聲電導能減輕化療導緻的消化道反應，該治療方法安全、有效。
목적：관찰혈위초성전도승백첩제대화료인기골수억제적예방작용。방법장90례접수상규화료적종류환자수궤분위치료조（A조）、대조조（B조）화공백조（C조），매조각30례。 A、B량조재화료전5 d개시진행족삼리화혈해혈적혈위초성전도치료，A조사용승백첩편；B조사용공백첩편，련속7 d；C조불접수기타간예。관찰화료후골수억제발생솔급소화도반응등정황。결과삼조총체골수억제발생솔유현저성차이，A조최저（A조40．0％、B조66．7％、C조70．0％，P＝0．035）；A조、B조총체악심발생솔균저우C조（분별위33．3％、36．7％、60．0％），재엄중악심발생솔방면체도료현저성차이（ A조10．0％、B조13．3％、C조33．3％，P＝0．044）；동양，A조화B조적총체구토발생솔역저우C조（A조26．7％、B조30．0％、C조56．7％，P＝0．032）。 A、B조미견국부피부출현피진、과민등불량반응。결론혈위초성전도승백첩가이유효예방화료인기적골수억제，주요감소경도골수억제적발생솔。차외，혈위초성전도능감경화료도치적소화도반응，해치료방법안전、유효。
Objective To evaluate the preventive effect of electrophonophoresis with Shenbai Patch via acupoint on chemotherapy-in-duced marrow depression.Methods Total ninety tumor patients given ordinal chemotherapy were randomized into group A, group B and group C equally.Sufferers in group A and B were administered electrophonophoresis via Foot Three Li or Xuehai acupoint five days before chemotherapy.The whole treatment was seven days and Group A was additionally given ShenBai Patch.Marrow depression and gastrointesti-nal reactions induced by chemotherapy were recorded later.Results There were significant differences in the total marrow depression rate among the three groups (P=0.035).Group A had the lowest counts with only 40.0% compared with Group B (66.7%) and Group C (70.0) .Both Group A and Group B showed less gastrointestinal reactions such as severe nausea ( Group A with 10.0% incidence VS Group B 13.3% VS Group C 33.3%, P=0.044 ) and vomiting ( Group A with 26.7% incidence VS Group B 30.0% VS Group C 56.7%, P=0.032).Furthermore, no skin rash or allergy was observed in Group A or Group B.Conclusion Electrophonophoresis with Shenbai Patch via acupoint can effectively prevent marrow depression induced by chemotherapy.Patients who would suffer mild marrow sup-pression may benefit more from the therapy.In addition, simple electrophonophoresis via acupoint may ease gastrointestinal reactions in chemotherapy to some extent.The therapeutic schedule is safe and efficacious.
