CAJ | 학술논문

目的：观察并分析不同类型的颈动脉斑块经生活方式干预、药物治疗后的效果。方法选取我院168例颈动脉单发斑块患者，按彩色多普勒超声检查斑块的回声强度进行分组，治疗上均给予抗血小板、降脂、控制血压血糖、饮食和运动干预等综合治疗，6个月后复查，评估不同回声的斑块的治疗效果。结果经过治疗，低回声斑块组和混合回声斑块组疗效相似，斑块总面积有明显缩小，差异有统计学意义（P＜0．05），部分斑块回声出现改变；而等回声斑块组与强回声斑块组疗效相似，斑块总面积无明显变化，差异无统计学意义（P＞0．05），斑块回声性质无变化。结论通过药物治疗和对动脉硬化高危因素进行干预，可以改变斑块性质，降低缺血性脑卒中的发病率。
목적：관찰병분석불동류형적경동맥반괴경생활방식간예、약물치료후적효과。방법선취아원168례경동맥단발반괴환자，안채색다보륵초성검사반괴적회성강도진행분조，치료상균급여항혈소판、강지、공제혈압혈당、음식화운동간예등종합치료，6개월후복사，평고불동회성적반괴적치료효과。결과경과치료，저회성반괴조화혼합회성반괴조료효상사，반괴총면적유명현축소，차이유통계학의의（P＜0．05），부분반괴회성출현개변；이등회성반괴조여강회성반괴조료효상사，반괴총면적무명현변화，차이무통계학의의（P＞0．05），반괴회성성질무변화。결론통과약물치료화대동맥경화고위인소진행간예，가이개변반괴성질，강저결혈성뇌졸중적발병솔。
Objective To observe the effect of different types of carotid atherosclerotic plaques by lifestyle intervention and drug treat-ment.Methods In our hospital 168 cases of solitary carotid plaque of patients, grouped by color ultrasound plaque echo intensity, treat-ment were given anti platelet, lipid, blood glucose, blood pressure control of diet and exercise intervention and other comprehensive treat-ment, 6 months after the review, assessment of therapeutic effect of different echo plaque.Results After treatment, low echo plaques group and mixed echo plaque group have similar efficacy, total plaque area is significantly reduced, the difference was statistically significant, some of the plaque echo appeared to change;and the equal echo plaque group similar to the strong echo of plaque group curative effect, the total plaque area had no obvious change, no statistically significant difference, plaque echo not change.Conclusion Drug treatment and intervention on atherosclerosis risk factors, can change the plaque, reduce the incidence of cerebral arterial thrombosis.