中华小儿外科杂志
中華小兒外科雜誌
중화소인외과잡지
CHINESE JOURNAL OF PEDIATRIC SURGERY
2015年
5期
322-325
,共4页
赵成鹏%段永福%周晓波%梅孝臣%李付奎
趙成鵬%段永福%週曉波%梅孝臣%李付奎
조성붕%단영복%주효파%매효신%리부규
骨肉瘤%儿童%肢体
骨肉瘤%兒童%肢體
골육류%인동%지체
Osteosarcoma%Child%Limbs
目的 探讨保肢手术在不同年龄儿童骨肉瘤中的应用方法与效果.方法 选取本院2007年6月至2009年6月收治的骨肉瘤患儿57例为儿童组(年龄≤11岁),其中生物重建方式治疗38例,假体置换方式治疗19例;同期选取本院收治的60例青少年骨肉瘤患者作为对照组(年龄≥12岁),其中生物重建方式治疗42例,假体置换方式治疗18例.临床手术治疗后观察二组患儿的预后与生存率,通过统计学处理比较总结最佳保肢手术治疗方法.结果 儿童组病例随访期间病死率为33.3％,1年生存率为(86.2±4.9)％,2年生存率为(70.2±6.8)％,3年生存率为(66.2±5.0)％,5年生存率为(57.4±4.3)％,与对照组比较差异有统计学意义(P＜0.05).结论 年龄因素对骨肉瘤的预后状况存在显著影响,而生物重建与假体置换均为儿童骨肉瘤的有效治疗方式.
目的 探討保肢手術在不同年齡兒童骨肉瘤中的應用方法與效果.方法 選取本院2007年6月至2009年6月收治的骨肉瘤患兒57例為兒童組(年齡≤11歲),其中生物重建方式治療38例,假體置換方式治療19例;同期選取本院收治的60例青少年骨肉瘤患者作為對照組(年齡≥12歲),其中生物重建方式治療42例,假體置換方式治療18例.臨床手術治療後觀察二組患兒的預後與生存率,通過統計學處理比較總結最佳保肢手術治療方法.結果 兒童組病例隨訪期間病死率為33.3％,1年生存率為(86.2±4.9)％,2年生存率為(70.2±6.8)％,3年生存率為(66.2±5.0)％,5年生存率為(57.4±4.3)％,與對照組比較差異有統計學意義(P＜0.05).結論 年齡因素對骨肉瘤的預後狀況存在顯著影響,而生物重建與假體置換均為兒童骨肉瘤的有效治療方式.
목적 탐토보지수술재불동년령인동골육류중적응용방법여효과.방법 선취본원2007년6월지2009년6월수치적골육류환인57례위인동조(년령≤11세),기중생물중건방식치료38례,가체치환방식치료19례;동기선취본원수치적60례청소년골육류환자작위대조조(년령≥12세),기중생물중건방식치료42례,가체치환방식치료18례.림상수술치료후관찰이조환인적예후여생존솔,통과통계학처리비교총결최가보지수술치료방법.결과 인동조병례수방기간병사솔위33.3％,1년생존솔위(86.2±4.9)％,2년생존솔위(70.2±6.8)％,3년생존솔위(66.2±5.0)％,5년생존솔위(57.4±4.3)％,여대조조비교차이유통계학의의(P＜0.05).결론 년령인소대골육류적예후상황존재현저영향,이생물중건여가체치환균위인동골육류적유효치료방식.
Objective To explore the effects of extremity salvage surgery of osteosarcoma in children of different ages.Methods A total of 57 children aged under 11 years with malignant osteosarcoma from June 2008 to June 2011 were selected into children group.And 38 cases underwent biological reconstruction while another 19 cases received prosthesis.For control group,60 adolescent patients aged above 12 years with malignant bone tumors during the same period were designated as control group.And 42 cases had biological reconstruction while 18 cases received prosthesis.The postoperative survival rates of three groups were observed.And the optimal extremity salvage surgery was summarized with statistical processing.Results During follow-ups,the mortality rate was 33.3％.And 1,2,3 and 5-year survival rates were (86.2 ± 4.9) ％,(70.2 ± 6.8) ％,(66.2 ± 5.0) ％ and (57.4 ± 4.3) ％ respectively.Significant differences existed with control group (P ＜ 0.05).However,the prognoses of groups A and B showed no statistical significance (P＞0.05).And the overall incidence of postoperative complications had no significant difference between groups A and B (23.7％ vs 31.6％,P＞0.05).Conclusions Age is a major prognostic factor for osteosarcoma.And extremity-sparing surgery and prosthetic reconstruction are effective treatments for children with osteosarcoma.
