CAJ | 학술논문

[目的]探讨益生菌结合行为干预对肠易激综合征病人免疫功能的影响。[方法]将120例肠易激综合征病人根据随机抽签原则分为治疗组与对照组各60例,两组均给予基于益生菌的治疗方案,对照组给予常规护理,治疗组给予积极的行为干预,干预周期为2个月。[结果]干预后治疗组有效率为96.7%,对照组有效率为95.0%,两组有效率比较差异无统计学意义(P>0.05)；干预后两组血清CD8+值明显下降,CD4+值明显升高(P<0.05),且治疗组血清CD8+和CD4+值与对照组比较差异有统计学意义(P<0.05)；两组干预后焦虑与抑郁评分明显低于干预前,且干预后治疗组焦虑与抑郁评分明显低于对照组(P<0.05)；干预后治疗组生理功能、生理职能、躯体疼痛和总体健康评分明显高于对照组(P<0.05)。[结论]益生菌治疗肠易激综合征具有较好的疗效,而行为干预的应用能促进免疫功能的提高,缓解焦虑与抑郁情绪,从而提高病人的生活质量。
[목적]탐토익생균결합행위간예대장역격종합정병인면역공능적영향。[방법]장120례장역격종합정병인근거수궤추첨원칙분위치료조여대조조각60례,량조균급여기우익생균적치료방안,대조조급여상규호리,치료조급여적겁적행위간예,간예주기위2개월。[결과]간예후치료조유효솔위96.7%,대조조유효솔위95.0%,량조유효솔비교차이무통계학의의(P>0.05)；간예후량조혈청CD8+치명현하강,CD4+치명현승고(P<0.05),차치료조혈청CD8+화CD4+치여대조조비교차이유통계학의의(P<0.05)；량조간예후초필여억욱평분명현저우간예전,차간예후치료조초필여억욱평분명현저우대조조(P<0.05)；간예후치료조생리공능、생리직능、구체동통화총체건강평분명현고우대조조(P<0.05)。[결론]익생균치료장역격종합정구유교호적료효,이행위간예적응용능촉진면역공능적제고,완해초필여억욱정서,종이제고병인적생활질량。
Objective:To probe into the influence of probiotics combined with behavioral intervention on the im-mune function of patients with irritable bowel syndrome.Methods:A total of 120 cases of patients with irritable bowel syndrome were divided into treatment group and control group according to the principle of random lot-tery,60 cases in each.The patients in both groups were given the treatment plan based on probiotics.The pa-tients in control group were given conventional nursing,but the patients in treatment group were given the posi-tive behavioral interventions,and the intervention circle period was 2 months.Results:The effective rate of treat-ment group after intervention was 9 6 .7%,and that in control group was 9 5 .0%,and there was no statistically significant difference in efficient rate between both groups(P>0.05).After the intervention,the CD8 + value in serum levels in both groups decreased significantly,CD4 + value increased significantly(P<0.05),and there was statistically significant difference in serum value of CD8 + and CD4 + after the intervention between both groups (P<0.05);after the intervention,anxiety and depression scores in two groups were significantly lower than that before intervention.The anxiety and depression scores in treatment group after the intervention were muen lower than that in control group(P<0.05).After the intervention,the scores of physiological function,physio-logical functions,physical pain and general health scores in treatment group were significantly higher than that in control group(P<0.05).Conclusion:Probiotics for treatment of patients with irritable bowel syndrome has good curative effect,and the application of behavioral intervention can improve the immunity function,relieve anxiety and depression,and then to enhance the patients’quality of life.