CAJ | 학술논문

目的：探讨连续腰丛神经阻滞术后镇痛对股骨颈骨折术后血中炎性因子平衡的影响。方法：将100例股骨颈骨折患者按随机数字表法分为连续腰丛神经阻滞术后镇痛(PCNA)组和患者自控静脉镇痛(PCIA)组，观察两组患者术后24h视觉模拟评分(VAS评分)；测定两组麻醉前、切皮后5min、手术结束时以及术后24～48 h血浆白细胞6(IL-6)、IL-10比值。结果：两组术后24～48hVAS评分差异无统计学意义(P＞0.05)。两组IL-6比值在麻醉前、切皮后5min、手术结束各时点比较，差异无统计学意义(P>0.05)；术后24～48hIL-6／IL-10连续腰丛神经阻滞术后镇痛(PCNA)组为(3.9±2.7)， PCIA组为(10.5±6.7)，两组比较差异有统计意义(P＜0.01)。结论：PCNA对股骨颈骨折术后炎性因子平衡的影响较小，有利于减轻炎症反应。
목적：탐토련속요총신경조체술후진통대고골경골절술후혈중염성인자평형적영향。방법：장100례고골경골절환자안수궤수자표법분위련속요총신경조체술후진통(PCNA)조화환자자공정맥진통(PCIA)조，관찰량조환자술후24h시각모의평분(VAS평분)；측정량조마취전、절피후5min、수술결속시이급술후24～48 h혈장백세포6(IL-6)、IL-10비치。결과：량조술후24～48hVAS평분차이무통계학의의(P＞0.05)。량조IL-6비치재마취전、절피후5min、수술결속각시점비교，차이무통계학의의(P>0.05)；술후24～48hIL-6／IL-10련속요총신경조체술후진통(PCNA)조위(3.9±2.7)， PCIA조위(10.5±6.7)，량조비교차이유통계의의(P＜0.01)。결론：PCNA대고골경골절술후염성인자평형적영향교소，유리우감경염증반응。
ObjectiveExplore the postoperative analgesia in continuous lumbar plexus nerve block for femoral neck fractures in the effect of inflammatory cytokines balance in the postoperative blood.Methods 100 patients with femoral neck fracture according to random number table method were randomly divided into continuous lumbar plexus nerve block analgesia (PCNA) and postoperative patient controlled intravenous analgesia (PCIA) group,Observe two groups of patients with postoperative 24 visual analogue scale (VAS score); The determination of the two groups before anesthesia, cut skin after 5 min, at the end of surgery and postoperative 24 ~ 48 h plasma leucocyte 6 (IL 6) and IL -10 ratio.Results Two groups of postoperative 24 ~ 48 hVAS score difference has no statistical significance (P > 0.05). Two groups of IL - 6 ratio before anesthesia, cut skin surgery after 5 rain, end each time, there was no statistically significant difference (P> 0.05); Postoperative 24 ~ 48 IL-6/ IL - 10 continuous lumbar plexus nerve block for postoperative analgesia (PCNA) group (3.9 ±2.7), (10.5±6.7) for PCIA group, are similar between the two groups have statistical significance (P < 0.01).ConclusionPCNA of femoral neck fracture has little effect on postoperative inflammatory cytokines balance, is helpful to reduce inflammation reaction.