CAJ | 학술논문

变应性鼻炎(allergic rhinitis，AR)是机体接触变应原后主要由IgE介导的鼻黏膜非感染性炎性疾病，属于Ⅰ型变态反应。AR病理过程中涉及多种免疫活性细胞和组织细胞，这些细胞可以合成或释放多种细胞因子与炎性介质。目前AR具体的发病机制尚未完全明确，白细胞介素是近些年研究的主要着眼点，对其进一步研究将为AR的防治带来新方案。
변응성비염(allergic rhinitis，AR)시궤체접촉변응원후주요유IgE개도적비점막비감염성염성질병，속우Ⅰ형변태반응。AR병리과정중섭급다충면역활성세포화조직세포，저사세포가이합성혹석방다충세포인자여염성개질。목전AR구체적발병궤제상미완전명학，백세포개소시근사년연구적주요착안점，대기진일보연구장위AR적방치대래신방안。
Allergic rhinitis(AR) is a noninfectious inflammatory disease of the nasal mucosa, is mediated by IgE after the body contact allergens, belong toⅠtype of allergy. In AR pathological process, involving a variety of immune active cells and tissue cells, these cells can synthesis or release a variety of cytokines and inflammatory mediators. At present, the AR specific pathogenesis is not fully clear. Interleukin is the main focus research in recent years, further research will bring a new scheme for AR control.