中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
11期
76-77
,共2页
静脉铁剂%肾性贫血%铁代谢%血液指标
靜脈鐵劑%腎性貧血%鐵代謝%血液指標
정맥철제%신성빈혈%철대사%혈액지표
intravenous iron%renal anemia%iron metabolism%indexes
目的：观察对肾性贫血使用静脉铁剂的临床疗效，探讨监测铁代谢血液指标等指标对治疗肾性贫血的临床意义。方法选择2012年6月至2013年6月收治的接受血液透析患者98例，按照随机数字表法分为两组，各49例。两组患者均采用常规血液透析治疗，对照组在此基础上口服琥珀酸亚铁，观察组在此基础上静脉注射右旋糖酐铁。观察两组患者治疗效果及铁代谢血液指标变化水平。结果治疗8周后观察组患者总有效率显著高于对照组（ P<0.05）；两组患者铁代谢血液指标比治疗前均显著升高（ P<0.05），治疗后观察组上升幅度均高于对照组（ P<0.05），但均未超过检测范围。结论肾性贫血使用静脉铁剂能有效提高治愈率，但使用时应严格监测铁代谢血液指标，严禁铁过载给患者带来不良反应。
目的：觀察對腎性貧血使用靜脈鐵劑的臨床療效，探討鑑測鐵代謝血液指標等指標對治療腎性貧血的臨床意義。方法選擇2012年6月至2013年6月收治的接受血液透析患者98例，按照隨機數字錶法分為兩組，各49例。兩組患者均採用常規血液透析治療，對照組在此基礎上口服琥珀痠亞鐵，觀察組在此基礎上靜脈註射右鏇糖酐鐵。觀察兩組患者治療效果及鐵代謝血液指標變化水平。結果治療8週後觀察組患者總有效率顯著高于對照組（ P<0.05）；兩組患者鐵代謝血液指標比治療前均顯著升高（ P<0.05），治療後觀察組上升幅度均高于對照組（ P<0.05），但均未超過檢測範圍。結論腎性貧血使用靜脈鐵劑能有效提高治愈率，但使用時應嚴格鑑測鐵代謝血液指標，嚴禁鐵過載給患者帶來不良反應。
목적：관찰대신성빈혈사용정맥철제적림상료효，탐토감측철대사혈액지표등지표대치료신성빈혈적림상의의。방법선택2012년6월지2013년6월수치적접수혈액투석환자98례，안조수궤수자표법분위량조，각49례。량조환자균채용상규혈액투석치료，대조조재차기출상구복호박산아철，관찰조재차기출상정맥주사우선당항철。관찰량조환자치료효과급철대사혈액지표변화수평。결과치료8주후관찰조환자총유효솔현저고우대조조（ P<0.05）；량조환자철대사혈액지표비치료전균현저승고（ P<0.05），치료후관찰조상승폭도균고우대조조（ P<0.05），단균미초과검측범위。결론신성빈혈사용정맥철제능유효제고치유솔，단사용시응엄격감측철대사혈액지표，엄금철과재급환자대래불량반응。
Objective To observe the clinical efficacy of proper use of intravenous iron in renal anemia, and to investigate the clinical significance of monitoring blood indexes of iron metabolism for the treatment of renal anemia. Methods 98 patients with hemodialysis in our hospital from June 2012 to June 2013 were selected and randomly divided into two groups according to the random number table, 49 cases in each group. Both the two groups were treated by the conventional hemodialysis. On this basis the control group took oral ferrous succinate, while the observation group was intravenously injected by iron dextran. The treatment effects and change of the levels in iron metabolism blood indexes were observed in the two groups. Results The total effective rate after 8-week treatment in the observation group was significantly higher than that in the control group with statistical difference ( P < 0. 05 );the iron metabolism blood indexes after treatment in the two groups were significantly increased compared with before treatment, the differences were statisti-cally significant ( P < 0. 05 ) . The increase amplitude of iron metabolism blood indexes after treatment in the observation group was high-er than that in the control group, the difference had statistical significance ( P < 0. 05 ) , but which did not exceed the detection range. Conclusion Using intravenous iron for renal anemia can effectively improve the cure rate. However, using iron preparations should strictly detect the iron metabolism blood indexes, the iron overload causing adverse reactions should be strictly prohibited.
