CAJ | 학술논문

研究不同激素组合处理对小鼠超数排卵及产仔性能的影响，以便获得适宜的超数排卵的激素使用剂量。分别用不同剂量孕马血清促性腺激素（PMSG）和人绒毛膜促性腺激素（HCG）注入小鼠体内进行超数排卵处理，比较激素处理后小鼠卵母细胞成熟率、产仔数、胎儿出生重及性别比。结果显示，5 IU PMSG+5 IU HCG剂量组和10 IU PMSG+10 IU HCG剂量组合相比较，卵母细胞成熟率差异不显著（P＞0.05），5 IU PMSG+5 IU HCG剂量组平均产仔数最高；10 IU PMSG+10 IU HCG剂量组的胎儿平均初生重最高，但产仔数少。综合以上，在实验中，5 IU PMSG+5 IU HCG剂量组合进行超排处理效果最好。
연구불동격소조합처리대소서초수배란급산자성능적영향，이편획득괄의적초수배란적격소사용제량。분별용불동제량잉마혈청촉성선격소（PMSG）화인융모막촉성선격소（HCG）주입소서체내진행초수배란처리，비교격소처리후소서란모세포성숙솔、산자수、태인출생중급성별비。결과현시，5 IU PMSG+5 IU HCG제량조화10 IU PMSG+10 IU HCG제량조합상비교，란모세포성숙솔차이불현저（P＞0.05），5 IU PMSG+5 IU HCG제량조평균산자수최고；10 IU PMSG+10 IU HCG제량조적태인평균초생중최고，단산자수소。종합이상，재실험중，5 IU PMSG+5 IU HCG제량조합진행초배처리효과최호。
The study was conducted to investigate the effects of different dose hormone on super-ovulation and reproductive performance in mice in order to get the better methods of super-ovulation. The mouse was treated by the different dose PMSG and HCG for super-ovulation to compare with mouse oocyte of maturation rate,litter size,fetal birth weight and sex ratio. The results showed that there was not significant maturation rate of mouse oocytes between 5 IU PMSG+5 IU HCG group and 10 IU PMSG+10 IU HCG group (P>0.05).5 IU PMSG+5 IU HCG group was the highest for average litter size in all groups,and 10 IU PMSG+10 IU HCG group was the highest in fetal mean birth weight,but the litter size was the lowest. In this study,5 IU PMSG+5 IU HCG group was better for mouse super-ovulation.