CAJ | 학술논문

目的：应用二维斑点追踪技术评价2型糖尿病患者左心室心肌纵向收缩功能早期改变。方法选取2型糖尿病患者60例(T 2DM组)及正常对照组60例，应用经胸二维超声、获取受检者心尖二腔观、三腔观、四腔观图像，记录左心室内膜及外膜心肌纵向收缩期峰值应变。结果 T 2DM组与正常对照组各常规超声心动图参数(左心室收缩末期内径、左心室舒张末期内径、左心室后壁舒张末期厚度、室间隔舒张末期厚度、左心室射血分数、左心室内径缩短率、左心室质量及左心室质量指数)差异均无统计学意义；与正常对照组比较，T 2DM组的左心室长轴内膜心肌纵向峰值应变均明显减低（P＜0.05），而外膜心肌只有后壁、下壁及后间隔纵向峰值应变明显减低（P＜0.05）。结论二维超声斑点追踪技术能发现常规超声心动图难以发现的糖尿病患者左心室早期心肌纵向收缩功能异常。
목적：응용이유반점추종기술평개2형당뇨병환자좌심실심기종향수축공능조기개변。방법선취2형당뇨병환자60례(T 2DM조)급정상대조조60례，응용경흉이유초성、획취수검자심첨이강관、삼강관、사강관도상，기록좌심실내막급외막심기종향수축기봉치응변。결과 T 2DM조여정상대조조각상규초성심동도삼수(좌심실수축말기내경、좌심실서장말기내경、좌심실후벽서장말기후도、실간격서장말기후도、좌심실사혈분수、좌심실내경축단솔、좌심실질량급좌심실질량지수)차이균무통계학의의；여정상대조조비교，T 2DM조적좌심실장축내막심기종향봉치응변균명현감저（P＜0.05），이외막심기지유후벽、하벽급후간격종향봉치응변명현감저（P＜0.05）。결론이유초성반점추종기술능발현상규초성심동도난이발현적당뇨병환자좌심실조기심기종향수축공능이상。
Objective To investigate the value of 2 D speckle tracking imaging(2 D-STI) in evaluating the early change of the longitudinal contractibility of left ventricle in type 2 diabetes mellitus(T 2DM) patients. Methods General echocardiography were done in 60 T 2DM patients and 60 normal subjects. Two-dimensional images were recorded from the apical two-chamber view, three-chamber view and four-chamber view respectively of LV for all studied subjects. The longitudinal peak systolic strain of endocardium and epicardium were measured in all of these views using special strain software.Results The measurements from general echocardiography(LVESD,LVEDD,PWd,IVSd,LVEF,LVFS,LVM,LVMI) between T 2DM and normal groups have no significant difference . Compared with normal group, endocardial longitudinal peak systolic strain of group T 2DM decreased significantly(P<0.05) in all segments of LV, which occurred only in a small part of segments about epicardial longitudinal peak systolic strain (P<0.05). Conclusion 2 D-STI longitudinal strain could detect the dysfunction of LV in T 2DM, which was difficult to be detected by general echocardiography.