CAJ | 학술논문

目的：评价Kato-Katz与醛醚法检测日本血吸虫病定性与定量的效果。方法以Kato-Katz与醛醚法联合检出的38例日本血吸虫卵阳性患者的结果为金标准，将Kato-Katz与醛醚法的检测结果分别与金标准进行比较。结果 Kato-Katz与醛醚法的虫卵阳性检出率分别为81.58%和89.47%，经四格表的确切概率法检验，差异无统计学意义(P＝0.795)；阳性患者的平均EPG，Kato-Katz法为醛醚法的3.6倍；但Kato-Katz法的材料费与标本制作费比醛醚法低2.33倍。结论日本血吸虫卵的检出率Kato-Katz与醛醚法相近，但血吸虫病感染度，Kato-Katz法的EPG值远高于醛醚法，在进行血吸虫病的定量研究时，应采用醛醚法为宜。
목적：평개Kato-Katz여철미법검측일본혈흡충병정성여정량적효과。방법이Kato-Katz여철미법연합검출적38례일본혈흡충란양성환자적결과위금표준，장Kato-Katz여철미법적검측결과분별여금표준진행비교。결과 Kato-Katz여철미법적충란양성검출솔분별위81.58%화89.47%，경사격표적학절개솔법검험，차이무통계학의의(P＝0.795)；양성환자적평균EPG，Kato-Katz법위철미법적3.6배；단Kato-Katz법적재료비여표본제작비비철미법저2.33배。결론일본혈흡충란적검출솔Kato-Katz여철미법상근，단혈흡충병감염도，Kato-Katz법적EPG치원고우철미법，재진행혈흡충병적정량연구시，응채용철미법위의。
Objective To evaluate the qualitative and quantitative effect of Kato-Katz and formol-ether concentration methods in diagnosis of Schistosomiasis japonica. Methods Kato-Katz and formol-ether concentration methods were respectively used to determine the findings by comparing with the positive results of Schistosoma japonicum eggs detected by the combined use of the two approaches in 38 cases as gold standard. Results Positive egg rate by Kato-Katz and formol-ether concentration technique was respectively 89.47%and 81.58%, and the difference was not significant after verification of the exact probability by fourfold and contingency table (P=0.795). By mean eggs per gram(EPG) of stool from the positively infected patients, the count by Kato-Katz method was 3.6 times of that by formol-ether concentration technique, and the cost of materials and specimen preparation was 2.33 times lower in Kato-Katz method than formol-ether concentra?tion. Conclusion Kata-Katz method has similar detection rate to formol-ether concentration for Schistosoma japonicum eggs, yet the former can result in higher EPG value in determination of the infection density than the latter. Given quantitative study of schistosomiasis, formol-ether concentration is appropriately recommended.