实用临床医学
實用臨床醫學
실용림상의학
Practical Clinical Medicine
2015年
4期
1-3,8
,共4页
慢性阻塞性肺疾病,急性加重期%通阳化瘀%调和营卫%BODE指数%中西医结合治疗
慢性阻塞性肺疾病,急性加重期%通暘化瘀%調和營衛%BODE指數%中西醫結閤治療
만성조새성폐질병,급성가중기%통양화어%조화영위%BODE지수%중서의결합치료
chronic obstructive pulmonary disease,acute exacerbation period%removing extravasated blood%harmonizing yingfen and weifen%BODE index%integrated Chinese and Western medicine
目的：探讨中西医结合治疗慢性阻塞性肺疾病急性加重期（AECOPD）的临床疗效。方法将60例 AE-COPD的患者按不同的治疗方法分为2组：治疗组（30例）和对照组（30例）。采用“GOLD”发布《慢性阻塞性肺疾病全球倡议》中 AECOPD的规范化治疗方案，吸入支气管舒张剂，视病情使用抗生素、支气管解痉剂、化痰药、扩血管药、强心药等。治疗组在上述西医治疗基础上联合中药通阳化瘀、调和营卫方。观察2组患者临床疗效，BODE评价系统指标：FEV1、呼吸困难分级、6分钟步行距离等治疗前后的变化。结果治疗组总有效率较对照组明显改善（P＜0．05）。2组治疗后BODE评分较治疗前均明显改善（P＜0．05），治疗组治疗后BODE评分较对照组明显改善（P＜0．05）。结论通阳化瘀、调和营卫法治疗 AECOPD可明显改善患者临床疗效、BODE评分，且无明显的不良反应，是一种治疗 AECOPD较理想的方法。
目的：探討中西醫結閤治療慢性阻塞性肺疾病急性加重期（AECOPD）的臨床療效。方法將60例 AE-COPD的患者按不同的治療方法分為2組：治療組（30例）和對照組（30例）。採用“GOLD”髮佈《慢性阻塞性肺疾病全毬倡議》中 AECOPD的規範化治療方案，吸入支氣管舒張劑，視病情使用抗生素、支氣管解痙劑、化痰藥、擴血管藥、彊心藥等。治療組在上述西醫治療基礎上聯閤中藥通暘化瘀、調和營衛方。觀察2組患者臨床療效，BODE評價繫統指標：FEV1、呼吸睏難分級、6分鐘步行距離等治療前後的變化。結果治療組總有效率較對照組明顯改善（P＜0．05）。2組治療後BODE評分較治療前均明顯改善（P＜0．05），治療組治療後BODE評分較對照組明顯改善（P＜0．05）。結論通暘化瘀、調和營衛法治療 AECOPD可明顯改善患者臨床療效、BODE評分，且無明顯的不良反應，是一種治療 AECOPD較理想的方法。
목적：탐토중서의결합치료만성조새성폐질병급성가중기（AECOPD）적림상료효。방법장60례 AE-COPD적환자안불동적치료방법분위2조：치료조（30례）화대조조（30례）。채용“GOLD”발포《만성조새성폐질병전구창의》중 AECOPD적규범화치료방안，흡입지기관서장제，시병정사용항생소、지기관해경제、화담약、확혈관약、강심약등。치료조재상술서의치료기출상연합중약통양화어、조화영위방。관찰2조환자림상료효，BODE평개계통지표：FEV1、호흡곤난분급、6분종보행거리등치료전후적변화。결과치료조총유효솔교대조조명현개선（P＜0．05）。2조치료후BODE평분교치료전균명현개선（P＜0．05），치료조치료후BODE평분교대조조명현개선（P＜0．05）。결론통양화어、조화영위법치료 AECOPD가명현개선환자림상료효、BODE평분，차무명현적불량반응，시일충치료 AECOPD교이상적방법。
ABSTRACT:Objective To investigate the clinical effect of integrated Chinese and Western medi-cine on acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods Sixty patients with AECOPD were divided into two groups:treatment group and control group,with 30 patients in each group.According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD),all patients were given standardized treatment for AECOPD,including inhalation of bronchodilators,appropriate antibiotics,bronchial spasmolytic agents,expectorant drugs,vasodila-tors,and cardiotonic drugs.In addition,patients in treatment group were treated with removing extravasated blood and harmonizing yingfen and weifen.Clinical efficacies were assessed in both groups.Moreover,BODE indexes,including forced expiratory volume in 1 second(FEV1),dyspnea grade and 6-minute walk distance,were observed before and after treatment.Results BODE score was significantly improved after treatment in both groups (P<0.05 ).Compared with control group,the total effective rate and BODE score were significantly improved in treatment group (P<0.05).Conclusion Removing extravasated blood and harmonizing yingfen and weifen can improve clinical efficacy and BODE score without obvious adverse reactions in patients with AE-COPD.Therefore,this method is an ideal treatment for AECOPD.
