CAJ | 학술논문

随着对胃食管反流病（ gastroesophageal reflux disease ， GERD）及其危害性认知的逐渐深入，GERD的疾病概念本身及治疗方法也发生革命性的变化。质子泵抑制剂的应用是GERD内科治疗的一个里程碑，而腹腔镜胃底折叠术和胃镜下食管下括约肌射频术的应用使GERD的治疗进入综合性治疗时代，胃镜下食管下括约肌射频治疗对于GERD的典型症状有良好的近、远期疗效，该技术进入中国后被成功应用于高位反流引起的食管外症状，且该技术较抗反流手术具有更简单和微创的特点，有广阔的应用前景。
수착대위식관반류병（ gastroesophageal reflux disease ， GERD）급기위해성인지적축점심입，GERD적질병개념본신급치료방법야발생혁명성적변화。질자빙억제제적응용시GERD내과치료적일개리정비，이복강경위저절첩술화위경하식관하괄약기사빈술적응용사GERD적치료진입종합성치료시대，위경하식관하괄약기사빈치료대우GERD적전형증상유량호적근、원기료효，해기술진입중국후피성공응용우고위반류인기적식관외증상，차해기술교항반류수술구유경간단화미창적특점，유엄활적응용전경。
[Summary] As the gradual deepening understanding of gastroesophageal reflux disease ( GERD ) , more extraesophageal symptoms are noted .The concept and therapeutic strategy for GERD has also undergone a quiet revolution over recent years .The application of proton pump inhibitor ( PPI) has been a landmark of medical treatment for GERD , and the invention of laparoscopic fundoplication and endoscopic radiofrequency energy delivery to the lower esophageal sphincter are marking a new era of comprehensive therapy for GERD .Good short and long term outcomes have been obtained since endoscopic radiofrequency energy delivery to the lower esophageal sphincter was applied on typical symptoms of GERD .Furthermore, the technique has also been successfully used in treating extraesophageal symptoms induced by proximal reflux in China .With more simple and less invasive features compared with anti-reflux surgery, the radiofrequency procedure has broad application prospects .