中华消化外科杂志
中華消化外科雜誌
중화소화외과잡지
CHINESE JOURNAL OF DIGESTIVE SURGERY
2015年
6期
445-448
,共4页
结直肠肿瘤%肝转移%围术期%治疗策略
結直腸腫瘤%肝轉移%圍術期%治療策略
결직장종류%간전이%위술기%치료책략
Colorectal neoplasms%Liver metastases%Perioperative period%Treatment strategy
肝转移是结直肠癌患者死亡的主要原因.手术是目前治疗结直肠癌肝转移的最佳手段.然而,在围术期如何合理选择个体化的化疗方案以及手术时机和手术方式一直存在争议.因此,如何通过多学科团队模式对结直肠癌肝转移患者及其术前检查结果进行全面评估,针对不同的治疗目标,将患者分为不同组别,明确各组不同的治疗目的,为患者选择合理的化疗和靶向治疗方案,确定手术时机(是同步切除还是分步切除)和手术方式(是微创手术还是开腹手术)是提高结直肠癌肝转移患者预后的关键.
肝轉移是結直腸癌患者死亡的主要原因.手術是目前治療結直腸癌肝轉移的最佳手段.然而,在圍術期如何閤理選擇箇體化的化療方案以及手術時機和手術方式一直存在爭議.因此,如何通過多學科糰隊模式對結直腸癌肝轉移患者及其術前檢查結果進行全麵評估,針對不同的治療目標,將患者分為不同組彆,明確各組不同的治療目的,為患者選擇閤理的化療和靶嚮治療方案,確定手術時機(是同步切除還是分步切除)和手術方式(是微創手術還是開腹手術)是提高結直腸癌肝轉移患者預後的關鍵.
간전이시결직장암환자사망적주요원인.수술시목전치료결직장암간전이적최가수단.연이,재위술기여하합리선택개체화적화료방안이급수술시궤화수술방식일직존재쟁의.인차,여하통과다학과단대모식대결직장암간전이환자급기술전검사결과진행전면평고,침대불동적치료목표,장환자분위불동조별,명학각조불동적치료목적,위환자선택합리적화료화파향치료방안,학정수술시궤(시동보절제환시분보절제)화수술방식(시미창수술환시개복수술)시제고결직장암간전이환자예후적관건.
Liver metastasis is the leading cause of death from colorectal cancer.Surgical treatment is so far the best choice for the treatment of colorectal liver metastases (CRLM).However,how to suitably select an individualized chemotherapy in perioperative period and surgical time and tool is still under controversy.Therefore,the key factors of improving the prognosis of patients with CRLM include overall evaluation of the patients and their preoperative examination outcomes,dividing patients into different groups based on different therapeutic goals,understanding different therapeutic goals of each group,selecting suitable chemotherapy and targeted therapy,ensuring surgical time (synchronous or stepwise resection) and tools (minimally invasive or open surgery) through multidisciplinary team model.
