中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2015年
12期
91-92,93
,共3页
清热养阴汤%维生素C注射液%雾化吸入%鼻咽癌%放射治疗%不良反应
清熱養陰湯%維生素C註射液%霧化吸入%鼻嚥癌%放射治療%不良反應
청열양음탕%유생소C주사액%무화흡입%비인암%방사치료%불량반응
Qingreyangyin Decoction%Vitamin C Injection%atomization inhalation%nasopharyngeal carcinoma%radiotherapy%adverse reaction
目的：观察雾化吸入自拟清热养阴汤和维生素C注射液配合护理防治鼻咽癌患者放疗口腔不良反应的临床疗效。方法选择医院2012年1月至2014年10月收治的鼻咽癌患者60例，随机分为观察组和对照组，各30例，均给予抗感染、止痛、营养支持等综合对症治疗和常规护理，观察组患者加用雾化吸入自拟清热养阴汤和维生素C注射液及相应护理干预。结果观察组Ⅱ级以上口干、味觉改变、吞咽困难、口咽部疼痛、口腔黏膜反应等急性不良反应发生率均低于对照组（ P<0.05）；观察组患者放疗不良反应出现晚于对照组，恢复快于对照组，生存质量优于对照组（ P<0.05）；观察组患者未发生与自拟清热养阴汤和维生素C注射液相关的不良反应，放射治疗和化学治疗不良反应发生率与对照组相当（ P ？0.05）。结论雾化吸入自拟清热养阴汤和维生素C注射液配合护理能防治鼻咽癌患者放射治疗的并发症，减缓出现反应时间，减轻口腔黏膜反应程度，提高生存质量，安全性高，值得临床推广。
目的：觀察霧化吸入自擬清熱養陰湯和維生素C註射液配閤護理防治鼻嚥癌患者放療口腔不良反應的臨床療效。方法選擇醫院2012年1月至2014年10月收治的鼻嚥癌患者60例，隨機分為觀察組和對照組，各30例，均給予抗感染、止痛、營養支持等綜閤對癥治療和常規護理，觀察組患者加用霧化吸入自擬清熱養陰湯和維生素C註射液及相應護理榦預。結果觀察組Ⅱ級以上口榦、味覺改變、吞嚥睏難、口嚥部疼痛、口腔黏膜反應等急性不良反應髮生率均低于對照組（ P<0.05）；觀察組患者放療不良反應齣現晚于對照組，恢複快于對照組，生存質量優于對照組（ P<0.05）；觀察組患者未髮生與自擬清熱養陰湯和維生素C註射液相關的不良反應，放射治療和化學治療不良反應髮生率與對照組相噹（ P ？0.05）。結論霧化吸入自擬清熱養陰湯和維生素C註射液配閤護理能防治鼻嚥癌患者放射治療的併髮癥，減緩齣現反應時間，減輕口腔黏膜反應程度，提高生存質量，安全性高，值得臨床推廣。
목적：관찰무화흡입자의청열양음탕화유생소C주사액배합호리방치비인암환자방료구강불량반응적림상료효。방법선택의원2012년1월지2014년10월수치적비인암환자60례，수궤분위관찰조화대조조，각30례，균급여항감염、지통、영양지지등종합대증치료화상규호리，관찰조환자가용무화흡입자의청열양음탕화유생소C주사액급상응호리간예。결과관찰조Ⅱ급이상구간、미각개변、탄인곤난、구인부동통、구강점막반응등급성불량반응발생솔균저우대조조（ P<0.05）；관찰조환자방료불량반응출현만우대조조，회복쾌우대조조，생존질량우우대조조（ P<0.05）；관찰조환자미발생여자의청열양음탕화유생소C주사액상관적불량반응，방사치료화화학치료불량반응발생솔여대조조상당（ P ？0.05）。결론무화흡입자의청열양음탕화유생소C주사액배합호리능방치비인암환자방사치료적병발증，감완출현반응시간，감경구강점막반응정도，제고생존질량，안전성고，치득림상추엄。
Objective To observe the clinical effect of atomization inhalation of self-designed Qingreyangying Decoction and Vitamin C Injection coordinated by the nursing care for preventing and treating oral adverse reactions caused by radiotherapy in the patients with nasopharyngeal carcinoma(NPC). Methods 60 patients with NPC in the hospital from January 2012 to October 2012 were selected and randomly divided into the observation group and the control group,30 cases in each group. All the patients were given the comprehen-sive symptomatic treatment of anti-infection,analgesia,nutrition support,etc. ,and routine care,but the observation group was added with the atomization inhalation of self-designed Qingreyangying Decoction and Vitamin C Injection,and corresponding nursing process. Results The number of the patients appearing more than grade Ⅱof acute adverse reactions such as dry mouth,taste sense change,dys-phagia,oropharyngeal pain and oral mucosa reaction in the observation group was lower than that in the control group( P < 0. 05);the appearance of radiotherapeutical adverse reactions in the observation group was later than that in the control group,while the recovery in the observation group was faster than that in the control group and the survival quality was superior to the control group ( P < 0. 05);no adverse reactions related with self-designed Qingreyangying Decoction and Vitamin C Injection in the observation group occurred,the occurrence rates of adverse reactions in the radiotherapy and chemotherapy in the observation group were similar to those in the control group without statistical differences( P ? 0. 05). Conclusion Atomization inhalation of self-designed Qingre Yangyin Decoction and Vitamin C Injection coordinated by the nursing care for preventing and treating the radiotherapeutical complica-tions in the patients with NPC,slows down the response time,lightens the degree of oral mucosa reaction,improves the survival quality, has high safety and is worth of clinical promotion.
