CAJ | 학술논문

目的：比较右美托咪定和瑞芬太尼对脑外伤患者术后谵妄的效果。方法：行急诊脑外伤手术的患者60例，按照随机数字表法分为两组：右美托咪定组(n=34)：患者静脉泵注右美托咪定0.2~0.8μg·kg-1·h-1；瑞芬太尼组(n=26)：患者静脉泵注瑞芬太尼1000~2500μg/h。每日采用重症监护中的意识障碍评价方法来评估谵妄发生率。结果：与瑞芬太尼组比较，右美托咪定组患者谵妄发生率明显降低(P<0.05)。两组患者拔管时间、重症监护室(ICU)入住时间、总住院时间及其它术后并发症等差异均无统计学意义(P>0.05)。结论：右美托咪定可明显降低脑外伤患者术后谵妄的发生率，可作为ICU一种有效的术后镇静药。
목적：비교우미탁미정화서분태니대뇌외상환자술후섬망적효과。방법：행급진뇌외상수술적환자60례，안조수궤수자표법분위량조：우미탁미정조(n=34)：환자정맥빙주우미탁미정0.2~0.8μg·kg-1·h-1；서분태니조(n=26)：환자정맥빙주서분태니1000~2500μg/h。매일채용중증감호중적의식장애평개방법래평고섬망발생솔。결과：여서분태니조비교，우미탁미정조환자섬망발생솔명현강저(P<0.05)。량조환자발관시간、중증감호실(ICU)입주시간、총주원시간급기타술후병발증등차이균무통계학의의(P>0.05)。결론：우미탁미정가명현강저뇌외상환자술후섬망적발생솔，가작위ICU일충유효적술후진정약。
Objective: To compare the clinical effects of dexmedetomidine and remifentanil in the treatment of postoperative delirium in patients with cerebral trauma. Methods:60 patients, who were treated with cerebral trauma, were divided into a dexmedetomidine group (n=34) and a ruifentaini group (n=26) according to the random number table method. Iintravenous infusion of 0.2~0.8 o kg-1 o h-1dexmedetomidine was implemented to patients in the observation group and Iintravenous infu-sion of ruifentaini was carried out on patients in the control group with1000 to 2500 Mu g/h. Consciousness evaluation method of the ICU was utilized for the comparison of the incidence of delirium. Results:Compared with the remifentanil group, the inci-dence of delirium of the dexmedetomidine group was significantly reduced (P<0.05) . No significant difference was examined in the aspects of the extubation time, the hospitalization duration of the patients in ICU, total hospitalization duration and other complications after the surgery of the two groups (P>0.05) . Conclusion:Dexmedetomidine can reduce the incidence of postop-erative delirium in patients who have been operated with the surgery of cerebral trauma. It can be used as an effective postoper-ative ICU sedatives.