CAJ | 학술논문

目的：探讨氯吡格雷与阿司匹林治疗冠心病的临床疗效及不良反应，为老年冠心病患者提供参考。方法：选取我院2013年1月至2014年1月收治的40例冠心病患者，将患者分成观察组及对照组，分别服用氯毗格雷药物及阿司匹林药物，观察治疗效果。结果：观察组及对照组患者治疗后心绞痛发生次数对比分析后，差异有统计学意义(x2=6.233，P<0.05）。对两组患者治疗后的血小板聚集情况对比分析后，发现观察组患者更低，差异有统计学意义(t=9.124， P<0.05)。观察组患者有1例患者出现不良反应，对照组患者有4例患者出现不良反应。结论：氯吡格雷药物能够对冠心病发挥良好的疗效，患者的安全性更高，值得临床推广。
목적：탐토록필격뢰여아사필림치료관심병적림상료효급불량반응，위노년관심병환자제공삼고。방법：선취아원2013년1월지2014년1월수치적40례관심병환자，장환자분성관찰조급대조조，분별복용록비격뢰약물급아사필림약물，관찰치료효과。결과：관찰조급대조조환자치료후심교통발생차수대비분석후，차이유통계학의의(x2=6.233，P<0.05）。대량조환자치료후적혈소판취집정황대비분석후，발현관찰조환자경저，차이유통계학의의(t=9.124， P<0.05)。관찰조환자유1례환자출현불량반응，대조조환자유4례환자출현불량반응。결론：록필격뢰약물능구대관심병발휘량호적료효，환자적안전성경고，치득림상추엄。
Objective: To investigate the clinical efficacy of clopidogrel and aspirin in the treatment of coronary heart disease and their adverse reactions, thus providing reference for the elderly patients with coronary heart disease. Methods: 40 patients, who were treated with coronary artery disease in our hospital from January 2013 to January 2014, were divided into an experimental group and a control group. Patients in the experimental group were treated with clopidogrel while those in the control group were treated with aspirin. Then the therapeutic effects of the two groups were observed and compared. Results:After the treatment, the incidences of stenocardia of the two groups have statistically significant difference (x2=6.233, P<0.05) . Platelet aggregation in the observation group was lower than that in the control group. Their difference was statistically significant (t=9.124, P<0.05) . One patient in the observation group was observed to have adverse reactions but four patients in the control group had adverse reactions. Conclusion:Clopidogrel is of excellent clinical effect on the treatment of coronary heart disease. As a result, it is worthy of promotion.