CAJ | 학술논문

目的：以柴嵩岩益肾助阳活血化浊法加味应用,治疗临床123例多囊卵巢综合征( polycystic ovarian syndrome,PCOS)患者,观察疗效。方法123例患者采用计算机中央随机法分为中药组和西药组(达英-35),其中中药组64例,西药组59例,均连续治疗2个疗程,每疗程3个月。观察两组患者治疗前后性激素水平和排卵情况。结果两组患者在治疗后血清睾酮、促黄体生成素水平均较治疗前显著下降(P<0．01),组间比较无显著差异(P>0．05)；西药组每月月经来潮均为激素撤退性出血,中药组在改善排卵功能作用方面较西药组具有显著优势。结论益肾助阳活血化浊法加味应用,能够改善PCOS患者性激素严重失衡状态,形成有质量的月经,提高患者的排卵功能。
목적：이시숭암익신조양활혈화탁법가미응용,치료림상123례다낭란소종합정( polycystic ovarian syndrome,PCOS)환자,관찰료효。방법123례환자채용계산궤중앙수궤법분위중약조화서약조(체영-35),기중중약조64례,서약조59례,균련속치료2개료정,매료정3개월。관찰량조환자치료전후성격소수평화배란정황。결과량조환자재치료후혈청고동、촉황체생성소수평균교치료전현저하강(P<0．01),조간비교무현저차이(P>0．05)；서약조매월월경래조균위격소철퇴성출혈,중약조재개선배란공능작용방면교서약조구유현저우세。결론익신조양활혈화탁법가미응용,능구개선PCOS환자성격소엄중실형상태,형성유질량적월경,제고환자적배란공능。
Objective This research was aimed at observing the curative effect of Chinese herbal treatment for 123 PCOS patients by modified application of replenishing the kidney and tonifying yang, invag-orating blood and resolving turbidity treating priciple. Method Total 123 patients were randomly divided in-to two groups with 64 patients in the Chinese medicine group and 59 in the western medicine group ( diane-35 group). Both groups took two courses of treatment continuously (three months for one course). Changes of sex hormone expressions levels ( testosterone, luteinizing hormone, and etc) , and ovulation function were an-alyzed. Results The expression levels of T, and LH were significantly reduced (P<0. 01), and there was no significant difference between the two groups on the curative effect of reducing the abnormally elevated ex-pression of T and LH (P>0. 05). Patients in western medicine group only had hormone withdrawal bleeding each month, while the ovulation function of the patients in Chinese medicine group was significantly im-proved. Conclusion The modified application of replenishing the kidney and tonifying yang, invagorating blood and resolving turbidity treating principle can effectively balance the levels of sex hormone, improve the ovulation function and menstruation quality, and increase the pregnancy rate of PCOS patients.