解放军护理杂志
解放軍護理雜誌
해방군호리잡지
NURSING JOURNAL OF CHINESE PEOPLE'S LIBERATION ARMY
2015年
9期
10-13
,共4页
癌症%化疗%恶心呕吐%危险因素
癌癥%化療%噁心嘔吐%危險因素
암증%화료%악심구토%위험인소
cancer%chemotherapy%nausea and vomiting%risk factor
目的：探讨肿瘤患者发生化疗诱导性恶心呕吐的危险因素,以期为筛选高危患者和制定预防措施提供临床依据.方法2012年1月至2013年5月,采用便利抽样法选取龙游县人民医院恶性肿瘤患者345名为研究对象,采用一般资料调查量表、状态-特质焦虑量表(statetrait anxiety inventory,STAI)和症状困扰量表(the symptom distress scale,SDS),对其进行调查,并采用单因素和 Logistic回归分析法分析.结果345名患者中有240例发生恶心呕吐,发生率为60．57％.单因素分析显示,不同年龄、性别、化疗周期、有无恶心呕吐史、焦虑、疼痛和是否应用铂类化疗药的患者,其诱导性恶心呕吐发生率的差异均有统计学意义(均P＜0．05).Logistic回归分析显示,年龄、女性、恶心呕吐史、焦虑、疼痛、应用铂类化疗药和化疗周期是恶心呕吐发生的危险因素.结论化疗诱导性恶心呕吐的发生与多种因素有关,化疗前采取一定的预防措施可降低其发生率,保证化疗的顺利进行并提高患者的生活质量.
目的：探討腫瘤患者髮生化療誘導性噁心嘔吐的危險因素,以期為篩選高危患者和製定預防措施提供臨床依據.方法2012年1月至2013年5月,採用便利抽樣法選取龍遊縣人民醫院噁性腫瘤患者345名為研究對象,採用一般資料調查量錶、狀態-特質焦慮量錶(statetrait anxiety inventory,STAI)和癥狀睏擾量錶(the symptom distress scale,SDS),對其進行調查,併採用單因素和 Logistic迴歸分析法分析.結果345名患者中有240例髮生噁心嘔吐,髮生率為60．57％.單因素分析顯示,不同年齡、性彆、化療週期、有無噁心嘔吐史、焦慮、疼痛和是否應用鉑類化療藥的患者,其誘導性噁心嘔吐髮生率的差異均有統計學意義(均P＜0．05).Logistic迴歸分析顯示,年齡、女性、噁心嘔吐史、焦慮、疼痛、應用鉑類化療藥和化療週期是噁心嘔吐髮生的危險因素.結論化療誘導性噁心嘔吐的髮生與多種因素有關,化療前採取一定的預防措施可降低其髮生率,保證化療的順利進行併提高患者的生活質量.
목적：탐토종류환자발생화료유도성악심구토적위험인소,이기위사선고위환자화제정예방조시제공림상의거.방법2012년1월지2013년5월,채용편리추양법선취룡유현인민의원악성종류환자345명위연구대상,채용일반자료조사량표、상태-특질초필량표(statetrait anxiety inventory,STAI)화증상곤우량표(the symptom distress scale,SDS),대기진행조사,병채용단인소화 Logistic회귀분석법분석.결과345명환자중유240례발생악심구토,발생솔위60．57％.단인소분석현시,불동년령、성별、화료주기、유무악심구토사、초필、동통화시부응용박류화료약적환자,기유도성악심구토발생솔적차이균유통계학의의(균P＜0．05).Logistic회귀분석현시,년령、녀성、악심구토사、초필、동통、응용박류화료약화화료주기시악심구토발생적위험인소.결론화료유도성악심구토적발생여다충인소유관,화료전채취일정적예방조시가강저기발생솔,보증화료적순리진행병제고환자적생활질량.
Objective To explore the risk factors of chemotherapy induced nausea and vomiting(CINV)in patients with cancer,to find out the high-risk patients,and to provide empirical evidence for clinical thera-py and nursing.Methods By convenience sampling,345 patients were selected and surveyed by general questionnaires,STAI and SDS.Univariate analysis and Logistic regression analysis were used to analyze the variables.Results Among the 345 patients,240 patients experienced CINV,the incidence rate was 60.57%. The univariate analysis showed that there were statistic significance of the incidence of induced CINV of patients with different age,gender,chemotherapy period,whether or not had CINY,anxiety,pain and whether or not took platinum chemotherapeutic drugs(all P<0.05).The multivariate logistic regression analysis revealed that the influencing factors included:age,female,history of CINV,anxiety ,pain,the applying of platinum chemotherapeutic drugs and the cycles of chemotherapy.Conclusion The incidence of CINV in cancer patients is associated with many factors.Preventive measures are favorable for reducing the incidence of CINV and improving patients’quality of life before chemotherapy.
