CAJ | 학술논문

目的：评价肝素钠与生理盐水对于静脉留置针的封管效果.方法计算机检索中国期刊全文数据库(CNKI)、万方数字化期刊全文数据库、中国生物医学文献数据库(CBM)及维普期刊资源整合服务平台等医学数据库中关于静脉留置针肝素钠封管与生理盐水封管效果比较的随机对照试验,并且筛选纳入文献的参考文献.由2名研究者对文献质量进行严格评价和资料提取,对符合质量标准的研究进行 Meta分析.结果共纳入12篇随机对照试验,包括1399名患者.Meta 分析结果表明,两种封管液对于静脉留置针的堵塞率(Z＝1．84,P＝0．07)、回血发生率(Z＝0．82,P＝0．41)、局部外渗率(Z＝1．39,P＝0．16)、局部静脉炎发生率(Z＝0．93,P＝0．35)及平均留置天数(Z＝1．15,P＝0．25)的效果比较,差异均无统计学意义.结论对于静脉留置针封管液,在效果相同的情况下,建议临床上推广使用生理盐水封管,其安全性更高,同时能减少患者的经济负担以及护士的工作量.
목적：평개간소납여생리염수대우정맥류치침적봉관효과.방법계산궤검색중국기간전문수거고(CNKI)、만방수자화기간전문수거고、중국생물의학문헌수거고(CBM)급유보기간자원정합복무평태등의학수거고중관우정맥류치침간소납봉관여생리염수봉관효과비교적수궤대조시험,병차사선납입문헌적삼고문헌.유2명연구자대문헌질량진행엄격평개화자료제취,대부합질량표준적연구진행 Meta분석.결과공납입12편수궤대조시험,포괄1399명환자.Meta 분석결과표명,량충봉관액대우정맥류치침적도새솔(Z＝1．84,P＝0．07)、회혈발생솔(Z＝0．82,P＝0．41)、국부외삼솔(Z＝1．39,P＝0．16)、국부정맥염발생솔(Z＝0．93,P＝0．35)급평균류치천수(Z＝1．15,P＝0．25)적효과비교,차이균무통계학의의.결론대우정맥류치침봉관액,재효과상동적정황하,건의림상상추엄사용생리염수봉관,기안전성경고,동시능감소환자적경제부담이급호사적공작량.
Objective To evaluate the effects of peripheral intravenous remaining needle sealing with hepa-rin and saline.Methods Randomized controlled trials(RCTs)related to intravenous remaining needle seal-ing with saline and heparin were collected through the databases such as CNKI,Wanfang,CBM and CKNI. The quality of studies was critically appraised and data were extracted by two reviewers independently,and analysis the data with Meta analysis.Results Twelve RCTs involving 1 3 9 9 patients were included.There was no significant difference between saline sealing and heparin sealing in plugging rate of intravenous re-maining needle(Z=1.84,P=0.07),blood return rate(Z=0.82,P=0.41),local leakage rate(Z=1.39,P=0.16), local phlebitis incidence(Z=0.93,P=0.35)and the average remaining time(Z=1.15,P=0.25).Conclusion The application of saline for intravenous remaining needle sealing is more safe and effective compared with heparin.It can significantly reduce economic burden of the patients and workload of the nurses.