中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2015年
3期
390-392
,共3页
克罗恩病%院内感染%危险因素
剋囉恩病%院內感染%危險因素
극라은병%원내감염%위험인소
Crohn’s disease%Nosocomial infection%Risk factor
目的：探讨克罗恩病（CD）患者并发医院感染相关因素，为临床诊疗工作提供参考。方法对住院治疗的120例CD患者的临床资料进行比较分析；与医院感染有显著差异的因素再进行多元Logistic回归分析。结果 CD患者医院感染率为38.3%（46/120），医院获得性肺炎为32.6%（15/46）；疾病行为、活动指数（CDAI）、营养不良、使用激素或免疫抑制剂等均是并发院内感染的危险因素（P均＜0.05），其OR值分别为2.25、3.62、2.82、2.18和2.58。结论对于克罗恩病，临床中应综合考虑上述危险因素，做好感染的预防、治疗和护理工作。
目的：探討剋囉恩病（CD）患者併髮醫院感染相關因素，為臨床診療工作提供參攷。方法對住院治療的120例CD患者的臨床資料進行比較分析；與醫院感染有顯著差異的因素再進行多元Logistic迴歸分析。結果 CD患者醫院感染率為38.3%（46/120），醫院穫得性肺炎為32.6%（15/46）；疾病行為、活動指數（CDAI）、營養不良、使用激素或免疫抑製劑等均是併髮院內感染的危險因素（P均＜0.05），其OR值分彆為2.25、3.62、2.82、2.18和2.58。結論對于剋囉恩病，臨床中應綜閤攷慮上述危險因素，做好感染的預防、治療和護理工作。
목적：탐토극라은병（CD）환자병발의원감염상관인소，위림상진료공작제공삼고。방법대주원치료적120례CD환자적림상자료진행비교분석；여의원감염유현저차이적인소재진행다원Logistic회귀분석。결과 CD환자의원감염솔위38.3%（46/120），의원획득성폐염위32.6%（15/46）；질병행위、활동지수（CDAI）、영양불량、사용격소혹면역억제제등균시병발원내감염적위험인소（P균＜0.05），기OR치분별위2.25、3.62、2.82、2.18화2.58。결론대우극라은병，림상중응종합고필상술위험인소，주호감염적예방、치료화호리공작。
Objective To explore the risk factors for Crohn’s disease (CD) patients with nosocomial infection, and to provide guidance for the clinical diagnosis and treatment. Methods The clinical data of 120 cases of CD were analyzed by using comparative analysis, retrospectively. The signiifcantly related factors with nosocomial infection were analyzed by a multivariable Logistic regression. Results The incidence rate with nosocomial infection was 38.3%, there was 32.6% (15/46) CD patient with hospital acquired pneumonia. The disease behavior, Crohn’s disease activity index (CDAI), malnutrition, the use of corticoid and the use of immunosuppressive agents were the risk factors of CD patient with nosocomial infection (P all<0.05), and the OR values were 2.25, 3.62, 2.82, 2.18 and 2.58, respectively. Conclusions It is necessary for the medical staff to comprehensively consider these risk factors and take effective prevention, treatment and nursing measures.
