临床误诊误治
臨床誤診誤治
림상오진오치
CLINICAL MISDIAGNOSIS & MISTHERAPY
2015年
6期
63-65
,共3页
喘息性支气管炎%儿童%硫酸镁%雾化吸入%输注,静脉内%对比研究
喘息性支氣管炎%兒童%硫痠鎂%霧化吸入%輸註,靜脈內%對比研究
천식성지기관염%인동%류산미%무화흡입%수주,정맥내%대비연구
Asthmatic bronchitis%Child%Magnesium sulfate%Inhalation%Infusion,intravenous%Comparative study
目的：观察硫酸镁不同给药途径辅治小儿喘息性支气管炎的临床效果。方法选择小儿喘息性支气管炎160例,随机分为对照组、实验1组、实验2组和实验3组,每组40例。对照组予抗病毒、解痉平喘等常规治疗；实验各组均在对照组治疗的基础上加用其他治疗：实验1组予雾化吸入MgSO4,实验2组予静脉滴注MgSO4,实验3组予雾化吸入沙丁胺醇联合布地奈德,比较各组临床效果和应用MgSO4两组的不良反应。结果实验各组症状体征消失时间、喘息消失时间、住院时间均较对照组明显缩短,差异均有统计学意义（P<0．05)；两两比较实验各组间差异均无统计学意义（P>0．05)。不良反应发生率实验1组为7．5%（3/40),实验2组为25．0%（10/40),差异有统计学意义（P<0．05)。结论在常规治疗基础上应用MgSO4可提高小儿喘息性支气管炎的治疗效果、缩短治疗时间,雾化吸入较静脉滴注安全性更高。
目的：觀察硫痠鎂不同給藥途徑輔治小兒喘息性支氣管炎的臨床效果。方法選擇小兒喘息性支氣管炎160例,隨機分為對照組、實驗1組、實驗2組和實驗3組,每組40例。對照組予抗病毒、解痙平喘等常規治療；實驗各組均在對照組治療的基礎上加用其他治療：實驗1組予霧化吸入MgSO4,實驗2組予靜脈滴註MgSO4,實驗3組予霧化吸入沙丁胺醇聯閤佈地奈德,比較各組臨床效果和應用MgSO4兩組的不良反應。結果實驗各組癥狀體徵消失時間、喘息消失時間、住院時間均較對照組明顯縮短,差異均有統計學意義（P<0．05)；兩兩比較實驗各組間差異均無統計學意義（P>0．05)。不良反應髮生率實驗1組為7．5%（3/40),實驗2組為25．0%（10/40),差異有統計學意義（P<0．05)。結論在常規治療基礎上應用MgSO4可提高小兒喘息性支氣管炎的治療效果、縮短治療時間,霧化吸入較靜脈滴註安全性更高。
목적：관찰류산미불동급약도경보치소인천식성지기관염적림상효과。방법선택소인천식성지기관염160례,수궤분위대조조、실험1조、실험2조화실험3조,매조40례。대조조여항병독、해경평천등상규치료；실험각조균재대조조치료적기출상가용기타치료：실험1조여무화흡입MgSO4,실험2조여정맥적주MgSO4,실험3조여무화흡입사정알순연합포지내덕,비교각조림상효과화응용MgSO4량조적불량반응。결과실험각조증상체정소실시간、천식소실시간、주원시간균교대조조명현축단,차이균유통계학의의（P<0．05)；량량비교실험각조간차이균무통계학의의（P>0．05)。불량반응발생솔실험1조위7．5%（3/40),실험2조위25．0%（10/40),차이유통계학의의（P<0．05)。결론재상규치료기출상응용MgSO4가제고소인천식성지기관염적치료효과、축단치료시간,무화흡입교정맥적주안전성경고。
Objective To observe the clinical effect of magnesium sulfate used with different administration route in infants with asthmatic bronchitis. Methods:160 infants with asthmatic bronchitis were selected and divided randomly into 4 groups (n=40) according to therapy;control group, experimental group Ⅰ, experimental group Ⅱ and experimental groupⅢ. Methods Infants in the control group were given the conventional treatment with anti-virus medication and spasmolysis, and infants in each experimental group were given other therapeutic schedules on the basis of control group. Infants in the ex-perimental groupⅠwere administered with inhaled MgSO4 on the basis of conventional treatment;Infants in the experimental group Ⅱ were given intravenous MgSO4 on the basis of conventional treatment;infants in the experimental groupⅢwere given the inhaled salbutamol combined with budesonide on the basis of conventional treatment. The clinical effect in the four groups and adverse reactions in two groups with MgSO4 were compared. Results The time of experimental groups in each observation index was shorter than that of control group, and the differences were significant(P<0. 05). The differences of time in each observation index, however, were not significant(P>0. 05)between any of the two groups and the experimental groups. The rate of adverse reactions in experimental group Ⅰ was 7. 5%(3/40) but the rate in experimental group Ⅱ was 25. 0%(10/40). The difference of adverse reaction in the two groups showed significant difference(P<0. 05). Conclusion MgSO4 in treatment of infant asthmatic bronchitis based on conventional therapy can improve the therapeutic effect and shorten the thera-peutic time. Moreover, inhaled MgSO4 is safer than intravenous style.
