中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2015年
15期
43-45
,共3页
细菌%多重耐药菌%分离%分布
細菌%多重耐藥菌%分離%分佈
세균%다중내약균%분리%분포
Bacteria%Multiple drug-resistant bacteria%Separated%Distribution
目的:了解本院多重耐药菌种类及分布情况,为临床治疗和控制医院感染提供依据。方法采用K-B法或ATB细菌鉴定分析仪,依据CLSI2010年标准进行鉴定和药物敏感试验。结果共分离到7681株细菌,以革兰阴性杆菌为主共5670株占74.0%,革兰阳性菌株1046株占13.7%,真菌940株(12.3%)。共分离出多重耐药菌968株,前5位多重耐药菌依次为产ESBLs大肠埃希菌共516株(53.3%)、非产酶大肠埃希菌169株(17.5%),产ESBLs肺炎克雷伯菌112株(11.6%),耐苯唑西林葡萄球菌(MRCNS)94株(9.7%),耐苯唑西林金黄色葡萄球菌(MRSA)76(7.9%),主要是分布在外科、儿科、ICU和内科。在标本分布中,居于前3位的标本是以儿科、ICU、内科痰液为主,共检出353株(36.5%),其次是外科腹腔脓液为主,共249株(25.7%)。结论我院引起医院感染部位多发生在脓液和下呼吸道,以产ESBLs的细菌为主,临床应合理使用抗菌药物,加强对外科、儿科和ICU等科室多重耐药菌的监测与控制,以减少多重耐药菌感染的发生及蔓延。
目的:瞭解本院多重耐藥菌種類及分佈情況,為臨床治療和控製醫院感染提供依據。方法採用K-B法或ATB細菌鑒定分析儀,依據CLSI2010年標準進行鑒定和藥物敏感試驗。結果共分離到7681株細菌,以革蘭陰性桿菌為主共5670株佔74.0%,革蘭暘性菌株1046株佔13.7%,真菌940株(12.3%)。共分離齣多重耐藥菌968株,前5位多重耐藥菌依次為產ESBLs大腸埃希菌共516株(53.3%)、非產酶大腸埃希菌169株(17.5%),產ESBLs肺炎剋雷伯菌112株(11.6%),耐苯唑西林葡萄毬菌(MRCNS)94株(9.7%),耐苯唑西林金黃色葡萄毬菌(MRSA)76(7.9%),主要是分佈在外科、兒科、ICU和內科。在標本分佈中,居于前3位的標本是以兒科、ICU、內科痰液為主,共檢齣353株(36.5%),其次是外科腹腔膿液為主,共249株(25.7%)。結論我院引起醫院感染部位多髮生在膿液和下呼吸道,以產ESBLs的細菌為主,臨床應閤理使用抗菌藥物,加彊對外科、兒科和ICU等科室多重耐藥菌的鑑測與控製,以減少多重耐藥菌感染的髮生及蔓延。
목적:료해본원다중내약균충류급분포정황,위림상치료화공제의원감염제공의거。방법채용K-B법혹ATB세균감정분석의,의거CLSI2010년표준진행감정화약물민감시험。결과공분리도7681주세균,이혁란음성간균위주공5670주점74.0%,혁란양성균주1046주점13.7%,진균940주(12.3%)。공분리출다중내약균968주,전5위다중내약균의차위산ESBLs대장애희균공516주(53.3%)、비산매대장애희균169주(17.5%),산ESBLs폐염극뢰백균112주(11.6%),내분서서림포도구균(MRCNS)94주(9.7%),내분서서림금황색포도구균(MRSA)76(7.9%),주요시분포재외과、인과、ICU화내과。재표본분포중,거우전3위적표본시이인과、ICU、내과담액위주,공검출353주(36.5%),기차시외과복강농액위주,공249주(25.7%)。결론아원인기의원감염부위다발생재농액화하호흡도,이산ESBLs적세균위주,림상응합리사용항균약물,가강대외과、인과화ICU등과실다중내약균적감측여공제,이감소다중내약균감염적발생급만연。
Objective?To?understand?our?multiple?drug-resistant?strains?of?type?and?distribution,?provide?the?basis?for?clinical?treatment?and?control?of?hospital?infection.?Methods?Using K-B or method of ATB bacteria identiifcation analyzer, according to the standard for identiifcation and drug sensitive test CLSI2010?years.?Results?7681?strains?bacteria?isolated,?mainly?gram-negative?bacilli?5670?strains?(74.0%),?gram?positive?strains?in?1046?strains?(13.7%),?fungus?940?strains?(12.3%).?A?total?of?968?strains?of?multi-resistant?bacteria?was?isolated,?top?5?of?multi-resistant?bacteria?produce?ESBLs?e.?coli,?a?total?of?516?strains?(53.3%),?the?enzyme?production,?E.coli?169?strains?(17.5%),?producing?ESBLs?112?strains?(11.6%),?pneumonia?klebsiella?bacteria?resistant?to?benzene?azole?Westwood?staphylococcus?(MRCNS),?94?strains?(9.7%),?benzene?azole?resistance?Westwood?staphylococcus?aureus?(MRSA),?76?(7.9%),?mainly?distributed?in?surgery,?pediatrics,?ICU,?and?medicine.?On?the?distribution?of?the?specimen,?the?top?three?specimens?in?pediatrics,?ICU,?internal?sputum?is?given?priority?to,?check?out?the?353?strains?(36.5%),?followed?by?surgical?abdominal?pus?is?given?priority?to,?a?total?of?249?strains?(25.7%).?Conclusion?Our?position?causes?the?hospital?infection?in?pus?and?lower?respiratory?tract,?give?priority?to?with?producing?ESBLs?bacteria,?clinical?should?be?rational?use?of?antimicrobial?agents,?strengthen?the?surgery,?pediatrics?and?ICU?department?of?multi-resistant?bacteria?such?as?monitoring?and?control,?to?reduce?the?infection?outbreak?and?spread?of?multi-resistant?bacteria.