中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2015年
15期
40-41
,共2页
中药%五苓散%急性脑梗死%药理作用
中藥%五苓散%急性腦梗死%藥理作用
중약%오령산%급성뇌경사%약리작용
Traditional Chinese medicine%Wulingsan%Acute cerebral infarction%Pharmacological action
目的:总结中药五苓散的临床药理作用,探讨中药五苓散治疗急性脑梗死的临床疗效。方法回顾性分析100例急性脑梗死患者的临床资料,按治疗方式的不同分为2组,各50例。对照组接受西医常规保守治疗,观察组接受西医常规保守治疗+中药五苓散。观察对比指标包括:清醒时间及清醒率;格拉斯哥预后评分(GOS)及发症发生率。结果观察组50例患者的平均清醒时间是(3.74±0.48)d,随访1个月后,观察组患者的清醒率达49例(98%),GCS评分(9.74±0.35)分;对照组50例患者的平均清醒时间是(6.13±0.79)d,随访1个月后,观察组患者的清醒率达40例(80%),GCS评分(7.58±0.49)分。观察组患者的平均清醒时间短于对照组,1个月清醒率显著大于对照组,GCS评分高于对照组,均有统计学差异(P<0.05)。随访1个月后,观察组患者的并发症发生率为10%,显著低于对照组患者36%,均有统计学差异(P<0.05)。结论采用中药五苓散治疗急性脑梗死,临床疗效显著,值得临床推广。
目的:總結中藥五苓散的臨床藥理作用,探討中藥五苓散治療急性腦梗死的臨床療效。方法迴顧性分析100例急性腦梗死患者的臨床資料,按治療方式的不同分為2組,各50例。對照組接受西醫常規保守治療,觀察組接受西醫常規保守治療+中藥五苓散。觀察對比指標包括:清醒時間及清醒率;格拉斯哥預後評分(GOS)及髮癥髮生率。結果觀察組50例患者的平均清醒時間是(3.74±0.48)d,隨訪1箇月後,觀察組患者的清醒率達49例(98%),GCS評分(9.74±0.35)分;對照組50例患者的平均清醒時間是(6.13±0.79)d,隨訪1箇月後,觀察組患者的清醒率達40例(80%),GCS評分(7.58±0.49)分。觀察組患者的平均清醒時間短于對照組,1箇月清醒率顯著大于對照組,GCS評分高于對照組,均有統計學差異(P<0.05)。隨訪1箇月後,觀察組患者的併髮癥髮生率為10%,顯著低于對照組患者36%,均有統計學差異(P<0.05)。結論採用中藥五苓散治療急性腦梗死,臨床療效顯著,值得臨床推廣。
목적:총결중약오령산적림상약리작용,탐토중약오령산치료급성뇌경사적림상료효。방법회고성분석100례급성뇌경사환자적림상자료,안치료방식적불동분위2조,각50례。대조조접수서의상규보수치료,관찰조접수서의상규보수치료+중약오령산。관찰대비지표포괄:청성시간급청성솔;격랍사가예후평분(GOS)급발증발생솔。결과관찰조50례환자적평균청성시간시(3.74±0.48)d,수방1개월후,관찰조환자적청성솔체49례(98%),GCS평분(9.74±0.35)분;대조조50례환자적평균청성시간시(6.13±0.79)d,수방1개월후,관찰조환자적청성솔체40례(80%),GCS평분(7.58±0.49)분。관찰조환자적평균청성시간단우대조조,1개월청성솔현저대우대조조,GCS평분고우대조조,균유통계학차이(P<0.05)。수방1개월후,관찰조환자적병발증발생솔위10%,현저저우대조조환자36%,균유통계학차이(P<0.05)。결론채용중약오령산치료급성뇌경사,림상료효현저,치득림상추엄。
Objective?To?summarize?the?clinical?pharmacological?effects?of?traditional?Chinese?medicine?wulingsan?,?to?study?the?clinical?curative?effect?of?Chinese?medicine?wulingsan?treating?acute?cerebral?infarction.?Methods?The?clinical?data?of?100?cases?of?patients?with?acute?cerebral?infarction?were?given?retrospective?analysis?,?according?to?the?different?treatment?methods?they?were?divided?into?2?groups,?50?cases?in?each.?The?control?group?received?routine?western?medicine?conservative?treatment,?the?observation?group?received?routine?western?medicine?conservative?treatment?plus?traditional?Chinese?medicine?Poria?five?powder.?Comparative?observation?of?indicators?include:?awake?time?and?wakefulness?rate;?Glasgow?outcome?score?(GOS)?and?the?incidence?of?complications.?Results?The?average?time?of?observation?group?of?50?patients?was?(3.74±0.48)d,?after?1?months?of?follow-up,?the?rate?of?patients?was?observed?in?49?cases?(98%),?GCS?score?(9.74±0.35)?average?time;?control?group?of?50?patients?was?(6.13±0.79)d,?after?1?months?of?follow-up,?to?observe?the?awake?rate?group?patients?of?40?cases?(80%),?GCS?score?(7.58±0.49).?Patients?in?the?observation?group?the?average?time?was?shorter?than?the?control?group,?1?months?sober?rate?was?significantly?greater?than?that?of?the?control?group,?GCS?was?higher?than?that?of?the?control?group,?there?were?significant?differences?between?the?(P<0.05).?After?1?months?of?follow-up,?patients?in?the?observation?group?the?incidence?of?complications?was?10%,?significantly?lower?than?the?control?group?of?36%?patients,?were?statistically?significant?difference?(P<0.05).?Conclusion?The?clinical?curative?effect?of?Chinese?medicine?wulingsan?in?treatment?of?acute?cerebral?infarction?is?distinct,?,?it?is?worth?the?clinical?promotion.