CAJ | 학술논문

目的：观察慢性阻塞性肺疾病急性发作期（AECOPD）的不同中医证型的各实验室指标（血常规、C反应蛋白、血浆D-二聚体、血气）的比较。方法通过慢性阻塞性肺疾病急性发作期患者按中医证候分型，分为痰热郁肺、痰浊阻肺、肺肾气虚、阳虚水泛、痰蒙神窍等5型，分别对比各证型患者在治疗前血常规、C反应蛋白、血浆D-二聚体、血气的水平，通过对比分析其临床意义。结果 AECOPD患者主要有痰热郁肺、痰浊阻肺和肺肾气虚三型，其中痰热郁肺患者的C反应蛋白、血浆D-二聚体、动脉血二氧化碳水平高于痰浊阻肺型，而痰浊阻型又高于肺肾气虚型，结果有统计学意义（P＜0.05）。结论慢性阻塞性肺疾病急性发作期主要表现为痰热郁肺、痰浊阻肺和肺肾气虚三种证型，痰热郁肺型患者的C反应蛋白、血浆D-二聚体、动脉血二氧化碳水平均高于其他两型患者，表明痰热郁肺型患者的炎性反应明显，更易引起高凝及二氧化碳的潴留。
목적：관찰만성조새성폐질병급성발작기（AECOPD）적불동중의증형적각실험실지표（혈상규、C반응단백、혈장D-이취체、혈기）적비교。방법통과만성조새성폐질병급성발작기환자안중의증후분형，분위담열욱폐、담탁조폐、폐신기허、양허수범、담몽신규등5형，분별대비각증형환자재치료전혈상규、C반응단백、혈장D-이취체、혈기적수평，통과대비분석기림상의의。결과 AECOPD환자주요유담열욱폐、담탁조폐화폐신기허삼형，기중담열욱폐환자적C반응단백、혈장D-이취체、동맥혈이양화탄수평고우담탁조폐형，이담탁조형우고우폐신기허형，결과유통계학의의（P＜0.05）。결론만성조새성폐질병급성발작기주요표현위담열욱폐、담탁조폐화폐신기허삼충증형，담열욱폐형환자적C반응단백、혈장D-이취체、동맥혈이양화탄수평균고우기타량형환자，표명담열욱폐형환자적염성반응명현，경역인기고응급이양화탄적저류。
Objective Acute phase of chronic obstructive pulmonary disease (AECOPD) of different TCM syndrome types of the laboratory indexes (routine blood, c-reactive protein and plasma D-dimer, blood gas) comparison. Methods By chronic obstructive pulmonary disease in patients with acute phase according to the TCM syndrome classiifcation, divided into phlegm yu lung heat, phlegm turbidity resistance lung, lung and kidney deifciency, Yang deifciency water lfooding, phlegm and ifve type of god and the oriifces, respectively compared to the different type patients before treatment of routine blood, c-reactive protein and the level of plasma D-dimer, blood gas, through the analysis of clinical signiifcance. Results AECOPD patients mainly have phlegm yu lung heat, phlegm turbidity resistance type lung and lung and kidney deifciency, phlegm heat depression in patients with lung of c-reactive protein, plasma D-dimer, arterial blood carbon dioxide levels higher than the lung phlegm turbidity resistance type, type and phlegm turbidity resistance is higher than that of lung and kidney deifciency type, the result was statistically signiifcant (P<0.05). Conclusion Chronic obstructive pulmonary disease in acute attack period mainly for phlegm yu lung heat, phlegm turbidity resistance lung and lung and kidney deifciency syndrome, phlegm heat depressive patients with type of plasma D-dimer, c-reactive protein and blood carbon dioxide levels are higher than other two patients, showed that phlegm heat type yu lung inlfammation in patients with obvious, are more likely to cause high condensation and carbon dioxide retention.