CAJ | 학술논문

目的：观察牵牛花综合征的全视野视网膜电图（ERG）、多焦视网膜电图（ mfERG）及视网膜光学相干断层扫描（OCT）的图像特征及临床意义。方法对临床确诊的牵牛花综合征患者组10例10眼和正常对照组10例10眼进行全视野ERG，mfERG与OCT检查，并对数据进行统计分析。结果牵牛花综合征患者组全视野ERG显示b波潜伏期与正常对照组相比显著延长且b波振幅显著降低，<0.05；mfERG各环的反应密度均低于正常对照组，<0.05，2～5环的潜伏期与正常对照组相比显著延长，<0.05。患者组OCT显示各象限视网膜神经纤维层（RNFL）厚度平均值显著低于正常对照组，<0.05，薄变量（差值）以下方象限最大，鼻侧象限最小，薄变率（百分比）以颞侧象限最大，鼻侧象限最小。结论 ERG与OCT相结合的方法既能反映牵牛花综合征患者视网膜功能的变化，又能从形态及组织病理方面对其视网膜结构进行精确的观察，为进一步研究其临床特征提供了重要手段。
목적：관찰견우화종합정적전시야시망막전도（ERG）、다초시망막전도（ mfERG）급시망막광학상간단층소묘（OCT）적도상특정급림상의의。방법대림상학진적견우화종합정환자조10례10안화정상대조조10례10안진행전시야ERG，mfERG여OCT검사，병대수거진행통계분석。결과견우화종합정환자조전시야ERG현시b파잠복기여정상대조조상비현저연장차b파진폭현저강저，<0.05；mfERG각배적반응밀도균저우정상대조조，<0.05，2～5배적잠복기여정상대조조상비현저연장，<0.05。환자조OCT현시각상한시망막신경섬유층（RNFL）후도평균치현저저우정상대조조，<0.05，박변량（차치）이하방상한최대，비측상한최소，박변솔（백분비）이섭측상한최대，비측상한최소。결론 ERG여OCT상결합적방법기능반영견우화종합정환자시망막공능적변화，우능종형태급조직병리방면대기시망막결구진행정학적관찰，위진일보연구기림상특정제공료중요수단。
Objective To observe the characteristics of global electroretinogram (ERG), multifocal elec-troretinogram (mfERG) and optical coherence tomonraphy (OCT) performed on the patients with morning-glory syndrome.Methods Ten morning-glory syndrome patients (10 eyes) and ten normal control subjects (10 eyes) were tested with global ERG,mfERG and OCT.The data were processed with software SPSS. Results ERG showed the latency of b wave was significantly prolonged and its amplitude was significantly reduced in the morning-glory syndrome group compared with normal control group.The response densities of five ring areas in morning-glory syn-drome were decreased while the latencies of ring 2 , ring 3,ring 4 and ring 5 were significantly prolonged com-pared with normal control group by mfERG. Retinal nerve fibre layer (RNFL) thickness of patients with morning-glory syndrome group were thinner than normal control group. Furthermore,the change of RNFL thickness in each quadrant was not equal.Conclusion ERG combined with OCT can not only reflect retinal function, but also reflect accurate observation of the retinal structure from the morphological and pathological aspects,which provide an im-portant means for further study on its clinical characteristics.