CAJ | 학술논문

目的：比较屈光不正性弱视儿童和正常儿童视网膜神经纤维层和黄斑中心凹厚度的差异。方法屈光不正性弱视儿童25例50眼，正常儿童24例48眼，采用第三代光相干断层成像术（OCT）对两组患者的黄斑中心凹厚度进行测量并比较两组黄斑中心凹厚度的差异。结果屈光不正弱视组患者的视网膜神经纤维层厚度121.32±8.06μm，较正常组儿童的视网膜中心凹厚度104.63±6.24μm明显增加，<0.05。屈光不正弱视组患者的视网膜黄斑中心凹厚度133.12±14.89μm较正常组儿童的视网膜中心凹厚度135.42±13.14μm无明显改变。Pearson相关分析结果显示，屈光不正弱视组视网膜神经纤维层平均厚度与患者眼轴无明显相关性，r=0.08，P>0.05，而正常组患者的视网膜神经纤维层平均厚度与眼轴呈明显相关，r=-0.42，P<0.05。结论屈光不正性弱视可影响患者的视网膜神经纤维层厚度。
목적：비교굴광불정성약시인동화정상인동시망막신경섬유층화황반중심요후도적차이。방법굴광불정성약시인동25례50안，정상인동24례48안，채용제삼대광상간단층성상술（OCT）대량조환자적황반중심요후도진행측량병비교량조황반중심요후도적차이。결과굴광불정약시조환자적시망막신경섬유층후도121.32±8.06μm，교정상조인동적시망막중심요후도104.63±6.24μm명현증가，<0.05。굴광불정약시조환자적시망막황반중심요후도133.12±14.89μm교정상조인동적시망막중심요후도135.42±13.14μm무명현개변。Pearson상관분석결과현시，굴광불정약시조시망막신경섬유층평균후도여환자안축무명현상관성，r=0.08，P>0.05，이정상조환자적시망막신경섬유층평균후도여안축정명현상관，r=-0.42，P<0.05。결론굴광불정성약시가영향환자적시망막신경섬유층후도。
Objective To compare the thickness of retinal nerve fiber layer (RNFL) and central fovea of macula in children with ametropic amblyopia. Methods A total of 25 children (50 eyes) with ametropic amblyopia and 24 normal children (48 eyes) were enrolled. Thickness of RNFL and central fovea of macula of all subjects were measured by the Optical Coherence Tomography and compared and analyzed. Results The average thickness of the RNFL of the ametropic amblyopia group 121.32±8.06μm was significantly higher than that of the normal group 104.63±6.24μm, <0.05. The average thicknesses of central fovea of macula of the ametropic amblyopia group 133.12±14.89μm was not significantly different from that of the normal group 135.42±13.14μm. No correlations were found between the average thicknesses of central fovea of macula and the axis in amblyopic eyes =0.08, >0.05. The average thicknesses of the retinal nerve fiber layer had a negative correlation with the axis in normal eyes,=-0.42, <0.05. Conclusion Thickness of the RNFL may be influenced by ametropic amblyopia.