CAJ | 학술논문

目的：探讨分析育龄妇女宫颈糜烂与高危型人乳头瘤病毒（HR－HPV）感染的关系。方法：选取治疗的150例患宫颈糜烂的育龄妇女作为研究对象，采用第二代杂交捕获技术对HR－HPV进行筛查，将HR－HPV的感染情况同宫颈糜烂的程度及类型进行统计学分析。结果：宫颈糜烂Ⅰ度、Ⅱ度、Ⅲ度的HR－HPV感染率分别为11．4％、35．6％和38．3％，单纯型、乳头型、颗粒型宫颈糜烂的HR－HPV感染率分别为16．3％、53．8％和24．2％，Ⅱ度和Ⅲ度宫颈糜烂的感染率较Ⅰ度宫颈糜烂具有显著性差异（ P ＜0．05），单纯型和颗粒型宫颈糜烂的感染率较乳头型具有显著性差异（ P ＜0．05）。结论：宫颈糜烂育龄妇女患者易感染HR－HPV，二者呈正相关。
목적：탐토분석육령부녀궁경미란여고위형인유두류병독（HR－HPV）감염적관계。방법：선취치료적150례환궁경미란적육령부녀작위연구대상，채용제이대잡교포획기술대HR－HPV진행사사，장HR－HPV적감염정황동궁경미란적정도급류형진행통계학분석。결과：궁경미란Ⅰ도、Ⅱ도、Ⅲ도적HR－HPV감염솔분별위11．4％、35．6％화38．3％，단순형、유두형、과립형궁경미란적HR－HPV감염솔분별위16．3％、53．8％화24．2％，Ⅱ도화Ⅲ도궁경미란적감염솔교Ⅰ도궁경미란구유현저성차이（ P ＜0．05），단순형화과립형궁경미란적감염솔교유두형구유현저성차이（ P ＜0．05）。결론：궁경미란육령부녀환자역감염HR－HPV，이자정정상관。
Objective:To study the correlation between cervical erosion in women of childbearing age and high risk human papillomavirus ( HR-HPV) infection.Methods:150 cases of cervical erosion in women of childbearing age were selected.HR-HPV was detected by using the Hybrid Capture and the correlation between HR-HPV infection and the degree and the type of cervical erosion were statistically analyzed .Results:The HR-HPV infection rates of cervical erosion degreeⅠ,Ⅱ,Ⅲwere 11.4 %, 35.6 %and 38.3 %respectively.Compared with the infection rate of cervical erosion degreeⅠ, the difference between that of degree Ⅱ and Ⅲ was significant ( P <0.05).The HR-HPV infection rates of simplex, papillary and granular cervical erosion were 16.3 %, 53.8 %and 24.2 %respectively.Compared with the infection rate of the papillary cervical erosion, the difference between that of the granular and simplex cervical erosion of degree was significant ( P <0.05).Conclusion:Pa-tients with cervical erosion is easily infected by HR -HPV and there is a positive correlation between them.