CAJ | 학술논문

目的：探讨急性肺栓塞的血浆肌钙蛋白T（cTnT）、B型脑钠肽前体（NT－proBNP）及心肌酶水平，为其诊断提供临床依据。方法收集2011年1月～2011年12月的64例急性肺栓塞患者发病48 h内的血液标本，并选取同期的64例健康体检者作对照。采用电化学发光法检测血浆cTnT、NT－proBNP水平，采用全自动生化分析仪检测心肌酶谱（天门冬氨酸氨基转移酶AST、肌酸激酶CK、乳酸脱氢酶LDH、肌酸激酶同工酶CK－MB）。结果急性肺栓塞患者cTnT、NT－proBNP和血浆心肌酶的水平均高于健康体检者，其中除CK－MB（ P＜0．05），其余均为P＜0．01。结论血浆cTnT、NT－proBNP及心肌酶谱联合检测可用于急性肺栓塞的诊断和预测。
목적：탐토급성폐전새적혈장기개단백T（cTnT）、B형뇌납태전체（NT－proBNP）급심기매수평，위기진단제공림상의거。방법수집2011년1월～2011년12월적64례급성폐전새환자발병48 h내적혈액표본，병선취동기적64례건강체검자작대조。채용전화학발광법검측혈장cTnT、NT－proBNP수평，채용전자동생화분석의검측심기매보（천문동안산안기전이매AST、기산격매CK、유산탈경매LDH、기산격매동공매CK－MB）。결과급성폐전새환자cTnT、NT－proBNP화혈장심기매적수평균고우건강체검자，기중제CK－MB（ P＜0．05），기여균위P＜0．01。결론혈장cTnT、NT－proBNP급심기매보연합검측가용우급성폐전새적진단화예측。
Objective To investigate the acute pulmonary embolism of plasma troponin T ( cTnT) , B type natriuretic peptide precursor ( NT -proBNP ) and myocardial enzyme levels, so as to provide clinical evidence for its diagno-sis.Methods We collected from 2011 January to 2011 December 64 cases of patients with acute pulmonary embolism in 48 h blood specimens, 64 healthy persons as control were selected. By electrochemiluminescence detection of plasma cTnT, NT-proBNP levels, the detection of myocardial enzymes of automatic biochemical analyzer spectrum ( aspartate amino transferase AST, creatine kinase CK, lactate dehydrogenase, creatine kinase isoenzyme LDH CK-MB).Results Of acute pulmonary embolism in patients with cTnT, plasma NT-proBNP and myocardial enzyme levels were higher than those in healthy volunteers, in addition to CK-MB (P<0.05), the others were P<0.01.Conclusions Plasma cTnT, NT-proBNP and myocardial enzyme spectrum detection can be used for the prediction and diagnosis of acute pul-monary embolism.