CAJ | 학술논문

目的：探讨肝内周围型胆管细胞癌(Intrahepatic peripheral cholangiocarcinoma,IHPCC)的MSCT表现及肿瘤标志物CA199与IHPCC的相关性，提高对IHPCC的认识。方法收集自2009年1月至今我院肝胆外科经手术术后病理确诊的IHPCC患者30例，肝良性病变(肝囊肿，肝内胆管结石等)30例。回顾性分析所有患者的MSCT诊断结果及CA199检测结果，综合评价MSCT与CA199在单独或联合诊断IHPCC中的应用效果。结果 MSCT诊断IHPCC的准确率为92.00%，特异度为80.00%；CA199诊断IHPCC的准确率为72.41%，特异度为69.70%；两种计数联合应用诊断IHPCC的准确率为100%，特异度为95.45%。结论 MSCT结合CA199联合检测，可显著增强对IHPCC患者的术前诊断水平。对于提取制定手术方式，指导术中及术后早期治疗具有重要指导意义。
목적：탐토간내주위형담관세포암(Intrahepatic peripheral cholangiocarcinoma,IHPCC)적MSCT표현급종류표지물CA199여IHPCC적상관성，제고대IHPCC적인식。방법수집자2009년1월지금아원간담외과경수술술후병리학진적IHPCC환자30례，간량성병변(간낭종，간내담관결석등)30례。회고성분석소유환자적MSCT진단결과급CA199검측결과，종합평개MSCT여CA199재단독혹연합진단IHPCC중적응용효과。결과 MSCT진단IHPCC적준학솔위92.00%，특이도위80.00%；CA199진단IHPCC적준학솔위72.41%，특이도위69.70%；량충계수연합응용진단IHPCC적준학솔위100%，특이도위95.45%。결론 MSCT결합CA199연합검측，가현저증강대IHPCC환자적술전진단수평。대우제취제정수술방식，지도술중급술후조기치료구유중요지도의의。
Objective To investigate the MSCT features of intrahepatic peripheral cholangiocarcinoma(IHPCC) and the correlation of tumor markers CA199 and IHPCC , improving the understanding of IHPCC. Methods From January 2009 to now, 30 patients with IHPCC(diagnosed by pathological examination)and 30 patients with liver benign lesion were studied. Retrospective analysis was applied for all the data including the results of MSCT and CA199. Comprehensive assessments were used to study the diagnose effect of united use of MSCT and CA199. Results For the diagnosis of IHPCC, accuray of MSCT alone was 92.00% while sensitivity 80.00%. As to CA199, the accuracy was 72.41% while sensitivity was 69.70%. When both indexes were used, the accuracy was 100% and sensitivity was 95.45%. Conclusion The combination of MSCT and CA199 significantly increased the accuracy and sensitivity of IHPCC before the surgery was done. This combination is of great importance for helping the surgeons in making surgery strategies and peri-operative therapy plans.