CAJ | 학술논문

炎症性肠病是一种表现为消化道特异性炎症的疾病，主要包括克罗恩病和溃疡性结肠炎。其发病原因涉及环境、遗传、免疫、感染等，具体原因尚未明确。近期研究发现，维生素 D 缺乏可能与炎症性肠病的发生相关。维生素 D 与维生素 D 受体结合后可通过改变肠道黏膜屏障，影响固有免疫和适应性免疫，进而影响炎症性肠病的发生发展。该文主要对维生素 D 与炎症性肠病的关系进行综述。
염증성장병시일충표현위소화도특이성염증적질병，주요포괄극라은병화궤양성결장염。기발병원인섭급배경、유전、면역、감염등，구체원인상미명학。근기연구발현，유생소 D 결핍가능여염증성장병적발생상관。유생소 D 여유생소 D 수체결합후가통과개변장도점막병장，영향고유면역화괄응성면역，진이영향염증성장병적발생발전。해문주요대유생소 D 여염증성장병적관계진행종술。
Inflammatory bowel disease (IBD)is manifested as specific gastrointesti-nal tract inflammation,mainly including Crohn's disease and ulcerative colitis.The exact etiol-ogy of IBD remains unclear,probably associated with environment,heredity,immunity and in-fection,etc.Recent studies have demonstrated that vitamin D deficiency is probably correlated with the incidence of IBD.The combination of vitamin D and vitamin D receptor can affect in-nate and adaptive immunity through altering intestinal mucosal barrier,thereby exerting an effect upon the incidence and development of IBD.This article briefly reviews the association between vitamin D and IBD.