CAJ | 학술논문

目的：探讨纤维支气管镜联用无创通气、药物治疗慢性阻塞性肺疾病急性加重期并呼吸衰竭、肺性脑病的临床疗效。方法68例呼吸内科行纤维支气管镜联用无创通气、药物治疗的慢性阻塞性肺疾病急性加重期并呼吸衰竭、肺性脑病患者，观察治疗前及治疗2 h、4 h、12 h后的血气分析变化及临床疗效。结果本组68例患者中55例（80.88%）临床症状、血气分析结果明显改善，与治疗前比较：pH值升高（P<0.05），动脉血二氧化碳分压水平降低（P<0.05），动脉血氧分压水平升高（P<0.05）。结论纤维支气管镜联用无创通气、药物治疗慢性阻塞性肺疾病急性加重期并呼吸衰竭、肺性脑病患者疗效确切，能迅速缓解患者症状。
목적：탐토섬유지기관경련용무창통기、약물치료만성조새성폐질병급성가중기병호흡쇠갈、폐성뇌병적림상료효。방법68례호흡내과행섬유지기관경련용무창통기、약물치료적만성조새성폐질병급성가중기병호흡쇠갈、폐성뇌병환자，관찰치료전급치료2 h、4 h、12 h후적혈기분석변화급림상료효。결과본조68례환자중55례（80.88%）림상증상、혈기분석결과명현개선，여치료전비교：pH치승고（P<0.05），동맥혈이양화탄분압수평강저（P<0.05），동맥혈양분압수평승고（P<0.05）。결론섬유지기관경련용무창통기、약물치료만성조새성폐질병급성가중기병호흡쇠갈、폐성뇌병환자료효학절，능신속완해환자증상。
ObjectiveTo investigate the clinical efficacy of bronchoscopy combined with noninvasive ventilation, medication treat AECOPD complicated with respiratory failure,pulmonary encepHalopathy.MethodThe treatment of bronchoscopy combined with noninvasive ventilation,medication was taken to 68 cases of AECOPD with respiratory failure,pulmonary encepHalopathy.Observing the blood gas analysis changes and clinical changes when take the treatment before and 2 h、4 h、24 h after.ResultsAmong the 68 patients treated with this method,the clinical symptom and blood gas analysis results of 55 cases(80.88%)improved significantly.Compared with no treatment:pH values increased(P<0.05),arterial partial pressure of carbon dioxide levels decreased(P<0.05),arterial oxygen levels increased (P<0.05).ConclusionThe treatment of bronchoscopy combined with noninvasive ventilation,medication is an effective method for AECOPD complicated with respiratory failure,pulmonary encepHalopathy,remitting clinical symptoms rapidly.