CAJ | 학술논문

目的：探讨血清蛋白电泳用于肝脏移植术后肝脏功能恢复及并发症监测中的临床应用价值。方法选取我院2013年3月至2013年6月期间接受肝移植手术的患者33例，检测受试者首次就诊及肝移植术后约1年时血清蛋白电泳各组分，分析移植前后各蛋白组分含量及异常蛋白的出现情况。结果肝脏移植后白蛋白组分含量明显高于移植前，而γ球蛋白组分含量低于移植前，且差异均有统计学意义（P均＜0.05）。α1、α2、β蛋白组分含量移植前后差异均无统计学意义（P均＞0.05）。移植前有9例谱带呈现β－γ桥；移植后γ球蛋白异常升高例数明显低于移植前，另有2例出现寡克隆带。结论分析肝脏移植患者血清蛋白电泳各成分变化可以监测移植后肝脏合成功能恢复及是否出现并发症。
목적：탐토혈청단백전영용우간장이식술후간장공능회복급병발증감측중적림상응용개치。방법선취아원2013년3월지2013년6월기간접수간이식수술적환자33례，검측수시자수차취진급간이식술후약1년시혈청단백전영각조분，분석이식전후각단백조분함량급이상단백적출현정황。결과간장이식후백단백조분함량명현고우이식전，이γ구단백조분함량저우이식전，차차이균유통계학의의（P균＜0.05）。α1、α2、β단백조분함량이식전후차이균무통계학의의（P균＞0.05）。이식전유9례보대정현β－γ교；이식후γ구단백이상승고례수명현저우이식전，령유2례출현과극륭대。결론분석간장이식환자혈청단백전영각성분변화가이감측이식후간장합성공능회복급시부출현병발증。
Objective To analyze the application value of serum protein electrophoresis for monitoring liver function recovery and complications after liver transplantation. Methods 33 cases of liver transplantation patients in our hospital from March 2013 to June 2013 were collected. Serum protein electrophoresis compo-nents of the patients were analyzed when first admission and about one year after transplantation. The protein constituent content and abnormal protein before and after transplantation were analyzed. Results Compared with pretransplant group, the albumin was higher, andγ-globulin component was lower significantly in post transplant group, and the differences all had statistical significance (Pall<0.05). There were no statistical sig-nificance in the differences of α1,α2 andβprotein constituent content between pretransplant group and post transplant group.β-γbridge was detected in 9 cases in pretransplant group. While the cases with abnormalγ-globulin component in post transplant group was less than that of pretransplant group , in which oligoclonal bands were detected in 2 cases. Conclusion The protein component analysis before and after transplantation by serum protein electrophoresis can monitor liver function recovery and complications of the liver transplanta-tion patients.