CAJ | 학술논문

目的：探讨持续血液净化（CRRT）治疗利尿剂抵抗急性失代偿性心力衰竭（ADHF）的临床疗效。方法：选取2012年1月30日-2014年6月30日本院收治的58例利尿剂抵抗急性失代偿性心力衰竭患者为研究对象，按治疗方法及治疗时机不同，分为对照组26例，采用其他常规心衰治疗，早期CRRT治疗组17例，常规CRRT治疗组15例，对比三组的治疗效果。结果：三组患者治疗后48 h呼吸频率、心率、血压、血氧饱和度等临床指标及肌酐下降幅度、尿量增加幅度、脑钠肽下降幅度比较差异均有统计学意义（P<0.05）。结论：采用持续血液净化治疗利尿剂抵抗急性失代偿性心力衰竭，可使患者临床指标维持在正常范围，加大肌酐下降幅度、尿量增加幅度及脑钠肽下降幅度，促进治疗效果，且早期进行持续血液净化治疗的效果更加明显，值得临床广泛应用。
목적：탐토지속혈액정화（CRRT）치료이뇨제저항급성실대상성심력쇠갈（ADHF）적림상료효。방법：선취2012년1월30일-2014년6월30일본원수치적58례이뇨제저항급성실대상성심력쇠갈환자위연구대상，안치료방법급치료시궤불동，분위대조조26례，채용기타상규심쇠치료，조기CRRT치료조17례，상규CRRT치료조15례，대비삼조적치료효과。결과：삼조환자치료후48 h호흡빈솔、심솔、혈압、혈양포화도등림상지표급기항하강폭도、뇨량증가폭도、뇌납태하강폭도비교차이균유통계학의의（P<0.05）。결론：채용지속혈액정화치료이뇨제저항급성실대상성심력쇠갈，가사환자림상지표유지재정상범위，가대기항하강폭도、뇨량증가폭도급뇌납태하강폭도，촉진치료효과，차조기진행지속혈액정화치료적효과경가명현，치득림상엄범응용。
Objective:To study and explore the clinical efficacy of continuous renal replacement treatment (CRRT) on acute decompensated heart failure (ADHF) of diuretic resistance.Method:Fifty patients with acute decompensated heart failure of diuretic resistance who were admitted by the hospital from January 30 2012 to June 30 2014 were selected as research subjects,they were divided into the control group (26 cases,other conventional treatment of heart failure),early CRRT treatment group (17 cases) and conventional CRRT treatment group (13 cases)according to different treatment methods and treatment opportunities,the treatment efficacies of patients in the three groups were compared.Result:The differences in mutual comparisons in the breathing rate,heart rate,blood pressure,blood oxygen saturation,creatinine drop,increase scope of urine and falling range of brain natriuretic peptide were statistically significant(P<0.05).Conclusion:ADHF applied on acute decompensated heart failure with diuretic resistance can maintain clinical indexes of patients within normal range,accelerate the decrease of creatinine,the increase of urine volume and the decrease of brain natriuretic peptide,which can promote therapeutic effects.The effect of early CRRT is more obvious,being worthy of wide application in clinical practices.