中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
17期
36-37,38
,共3页
血清转铁蛋白%C反应蛋白%新生儿黄疸%临床意义
血清轉鐵蛋白%C反應蛋白%新生兒黃疸%臨床意義
혈청전철단백%C반응단백%신생인황달%림상의의
Serum transferrin%C reactive protein%Neonatal jaundice%Clinical significance
目的：探讨血清转铁蛋白（TRF）与C-反应蛋白（CRP）在新生儿黄疸中的变化及临床意义。方法：选取2013年3月-2014年3月来本院就诊的新生儿黄疸100例，按新生儿黄疸原因及总胆红素水平进行分组。选取同时间段生产的足月、无黄疸新生儿50例为对照组。对不同分组患儿的血清TRF和CRP水平进行比较。结果：感染因素组、围产因素组及其他因素组血清TRF和CRP水平与对照组比较差异均有统计学意义（P<0.05）；但三组间血清TRF比较差异无统计学意义（P>0.05）；感染因素组CRP水平明显高于围产因素组及其他因素组，差异均有统计学意义（P<0.05）。轻度黄疸组、中度黄疸组及重度黄疸组血清TRF和CRP水平与对照组比较差异均有统计学意义（P<0.05）；但三组间血清TRF比较差异无统计学意义（P>0.05）；重度黄疸组CRP水平明显高于轻、中度黄疸组，差异均有统计学意义（P<0.05）。结论：血清TRF和CRP水平对帮助新生儿黄疸的病因鉴别和疾病演变有一定的临床价值。
目的：探討血清轉鐵蛋白（TRF）與C-反應蛋白（CRP）在新生兒黃疸中的變化及臨床意義。方法：選取2013年3月-2014年3月來本院就診的新生兒黃疸100例，按新生兒黃疸原因及總膽紅素水平進行分組。選取同時間段生產的足月、無黃疸新生兒50例為對照組。對不同分組患兒的血清TRF和CRP水平進行比較。結果：感染因素組、圍產因素組及其他因素組血清TRF和CRP水平與對照組比較差異均有統計學意義（P<0.05）；但三組間血清TRF比較差異無統計學意義（P>0.05）；感染因素組CRP水平明顯高于圍產因素組及其他因素組，差異均有統計學意義（P<0.05）。輕度黃疸組、中度黃疸組及重度黃疸組血清TRF和CRP水平與對照組比較差異均有統計學意義（P<0.05）；但三組間血清TRF比較差異無統計學意義（P>0.05）；重度黃疸組CRP水平明顯高于輕、中度黃疸組，差異均有統計學意義（P<0.05）。結論：血清TRF和CRP水平對幫助新生兒黃疸的病因鑒彆和疾病縯變有一定的臨床價值。
목적：탐토혈청전철단백（TRF）여C-반응단백（CRP）재신생인황달중적변화급림상의의。방법：선취2013년3월-2014년3월래본원취진적신생인황달100례，안신생인황달원인급총담홍소수평진행분조。선취동시간단생산적족월、무황달신생인50례위대조조。대불동분조환인적혈청TRF화CRP수평진행비교。결과：감염인소조、위산인소조급기타인소조혈청TRF화CRP수평여대조조비교차이균유통계학의의（P<0.05）；단삼조간혈청TRF비교차이무통계학의의（P>0.05）；감염인소조CRP수평명현고우위산인소조급기타인소조，차이균유통계학의의（P<0.05）。경도황달조、중도황달조급중도황달조혈청TRF화CRP수평여대조조비교차이균유통계학의의（P<0.05）；단삼조간혈청TRF비교차이무통계학의의（P>0.05）；중도황달조CRP수평명현고우경、중도황달조，차이균유통계학의의（P<0.05）。결론：혈청TRF화CRP수평대방조신생인황달적병인감별화질병연변유일정적림상개치。
Objective:To explore the changes and clinical significance of serum transferrin and C reactive protein in neonatal jaundice.Method:100 cases of neonatal jaundice were selected from March 2013 to March 2014 in our hospital and were grouped according to the causes and total bilirubin levels of neonatal jaundice.50 full-term and no jaundice newborns were selected as control group during the same time period.The serum TRF and CRP levels of children in different group were completed.Result:The serum TRF and CRP levels of infection factors group,perinatal factors group and other factors group compared with the control group,the differences were statistically significant(P<0.05).But there was no significant difference in the serum TRF levels among the three groups(P>0.05).C reactive protein level of infection factors group was significantly higher than perinatal factors group and other factors group,the differences were statistically significant(P<0.05).The serum TRF and CRP levels of mild jaundice group,moderate jaundice group and severe jaundice group compared with the control group,the differences were statistically significant(P<0.05).But there was no significant difference in the serum TRF level among the three groups(P>0.05).C reactive protein level of severe jaundice group was significantly higher than mild,moderate jaundice group,the differences were statistically significant(P<0.05).Conclusion:Serum TRF and CRP levels have certain clinical value in differentiating etiology and disease of neonatal jaundice.
