农药学学报
農藥學學報
농약학학보
CHINESE JOURNAL OF PESTICIDE SCIENCE
2015年
3期
307-312
,共6页
石凯威%汤丛峰%李莉%刘丰茂
石凱威%湯叢峰%李莉%劉豐茂
석개위%탕총봉%리리%류봉무
叶菌唑%小麦%消解动态%残留%风险评价
葉菌唑%小麥%消解動態%殘留%風險評價
협균서%소맥%소해동태%잔류%풍험평개
metconazole%wheat%dissipation%residue%risk assessment
为评价叶菌唑在小麦中的残留行为及其产生的膳食摄入风险，于北京、安徽及黑龙江进行了1年3地田间试验，建立了叶菌唑在小麦中的残留分析方法，并对我国不同人群的膳食暴露风险进行了评价。样品用乙腈提取，经Florisil固相萃取柱净化，气相色谱-氮磷检测器（ GC-NPD）检测，外标法定量。结果表明：在0.02～10 mg／kg的添加水平下，叶菌唑在小麦籽粒和植株中的平均回收率在81％～101％之间，相对标准偏差（ RSD）在2.1％～9.1％之间；其在小麦籽粒和植株中的定量限（ LOQ）分别为0.02和0.04 mg／kg。叶菌唑在小麦植株中的消解符合一级动力学方程，半衰期为4.9～7.3 d。收获时小麦籽粒中叶菌唑的最大残留量为0.037 mg／kg，低于美国和欧盟设定的最大残留限量（ MRL）0.15 mg／kg。针对我国不同人群的膳食摄入及风险评估暴露，风险商值（ RQ）在0.001～0.002之间，表明叶菌唑在小麦中的膳食摄入风险较低。
為評價葉菌唑在小麥中的殘留行為及其產生的膳食攝入風險，于北京、安徽及黑龍江進行瞭1年3地田間試驗，建立瞭葉菌唑在小麥中的殘留分析方法，併對我國不同人群的膳食暴露風險進行瞭評價。樣品用乙腈提取，經Florisil固相萃取柱淨化，氣相色譜-氮燐檢測器（ GC-NPD）檢測，外標法定量。結果錶明：在0.02～10 mg／kg的添加水平下，葉菌唑在小麥籽粒和植株中的平均迴收率在81％～101％之間，相對標準偏差（ RSD）在2.1％～9.1％之間；其在小麥籽粒和植株中的定量限（ LOQ）分彆為0.02和0.04 mg／kg。葉菌唑在小麥植株中的消解符閤一級動力學方程，半衰期為4.9～7.3 d。收穫時小麥籽粒中葉菌唑的最大殘留量為0.037 mg／kg，低于美國和歐盟設定的最大殘留限量（ MRL）0.15 mg／kg。針對我國不同人群的膳食攝入及風險評估暴露，風險商值（ RQ）在0.001～0.002之間，錶明葉菌唑在小麥中的膳食攝入風險較低。
위평개협균서재소맥중적잔류행위급기산생적선식섭입풍험，우북경、안휘급흑룡강진행료1년3지전간시험，건립료협균서재소맥중적잔류분석방법，병대아국불동인군적선식폭로풍험진행료평개。양품용을정제취，경Florisil고상췌취주정화，기상색보-담린검측기（ GC-NPD）검측，외표법정량。결과표명：재0.02～10 mg／kg적첨가수평하，협균서재소맥자립화식주중적평균회수솔재81％～101％지간，상대표준편차（ RSD）재2.1％～9.1％지간；기재소맥자립화식주중적정량한（ LOQ）분별위0.02화0.04 mg／kg。협균서재소맥식주중적소해부합일급동역학방정，반쇠기위4.9～7.3 d。수획시소맥자립중협균서적최대잔류량위0.037 mg／kg，저우미국화구맹설정적최대잔류한량（ MRL）0.15 mg／kg。침대아국불동인군적선식섭입급풍험평고폭로，풍험상치（ RQ）재0.001～0.002지간，표명협균서재소맥중적선식섭입풍험교저。
In order to evaluate the residue behavior and dietary intake risk of metconazole applied to wheat,the residual trial of metconazole in wheat were carried out in Beijing,Anhui and Heilongjiang provinces. A new method was developed to determine the residue of metconazole in wheat. The risk assessment to different populations based on data of terminal residues in wheat was investigated. The samples were extracted with acetonitrile,purified by florisil SPE column,and determined by gas chromatography coupled with nitrogen phosphorus detector( NPD ). At fortified levels of 0. 02 -10 mg/kg,recoveries of metconazole in wheat and straw were between 81% -101%,with RSD of 2. 14% -9. 10%. The limits of quantification( LOQs)were 0. 02 mg/kg in grain,0. 04 mg/kg in straw. The results indicated that the dissipation of metconazole in straw fitted to the first order kinetics with half-lives of 4. 9-7. 3 days. At harvest period,the highest residue of metconazole in grain was 0. 037 mg/kg,which was lower than the maximum residue limit( MRL,0. 15 mg/kg)set by the United States and European Union. The risk quotients( RQs ) were between 0. 001 - 0. 002 for different populations in China,which indicated its low risk in wheat.
