CAJ | 학술논문

新型异唑啉类杀虫剂fluralaner通过干扰γ-氨基丁酸（ GABA）门控氯离子通道发挥作用。作为新型高效GABA门控氯离子通道干扰剂，与环戊二烯类、苯基吡唑类和大环内酯类杀虫剂相比，fluralaner在分子结构、作用位点、选择性以及交互抗性等方面均有显著差异。本文综述了fluralaner及其衍生物的研发、毒性、防治范围以及作用机理等，并预测了其应用前景。
신형이서람류살충제fluralaner통과간우γ-안기정산（ GABA）문공록리자통도발휘작용。작위신형고효GABA문공록리자통도간우제，여배무이희류、분기필서류화대배내지류살충제상비，fluralaner재분자결구、작용위점、선택성이급교호항성등방면균유현저차이。본문종술료fluralaner급기연생물적연발、독성、방치범위이급작용궤리등，병예측료기응용전경。
Fluralaner acts as a novel type of isoxazoline insecticides by interfere with γ-aminobutyric acid( GABA)gated chloride channel. It displays remarkable differences in molecular structure,site of action,selectivity and cross-resistance comparing to cyclodience, phenylpyrazole and macrolides insecticides which have similar mode of action in interfering with GABA gated chloride channel. The invention,toxicity,insecticidal spectrum and mechanism of fluralaner were summarized. The prospect of fluralaner and isoxazoline insecticides were also included.