CAJ | 학술논문

水体、土壤等环境污染近年来呈加剧趋势,严重影响食物质量安全,威胁人类健康,环境污染物及其毒性效应研究越来越受到重视。谷胱甘肽硫转移酶(glutathione S-transferase, GST)作为分子水平上的生物标记物,由于具有特异性和预警性等特点受到广泛关注,在水体和土壤等环境生态风险评估中具有巨大的应用潜力。本文综述了GST作为指示环境污染早期预警指标的生态毒理学机制以及其对环境污染物的响应研究现状,指出了目前应用中存在的问题,并展望了其在环境风险评价中的发展趋势。
수체、토양등배경오염근년래정가극추세,엄중영향식물질량안전,위협인류건강,배경오염물급기독성효응연구월래월수도중시。곡광감태류전이매(glutathione S-transferase, GST)작위분자수평상적생물표기물,유우구유특이성화예경성등특점수도엄범관주,재수체화토양등배경생태풍험평고중구유거대적응용잠력。본문종술료GST작위지시배경오염조기예경지표적생태독이학궤제이급기대배경오염물적향응연구현상,지출료목전응용중존재적문제,병전망료기재배경풍험평개중적발전추세。
Water, soil and other environmental pollution trends were exacerbated in recent years, which affected food quality and safety and threatened human health seriously. Environmental pollutants and their toxic effects had been paid more and more attention. Glutathione S-transferase enzyme (GST) attracted concerns widespreadly as a biomarker in the molecular level due to its specific and warning characteristics, and it had a huge potential application in water and soil risk assessment. This paper reviewed the mechanism of GST as an early warning indicator of environmental pollutions and its response, pointed out the problems in the current application, and looked into the prospect of its environmental risk assessment trends.