世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2015年
6期
928-931
,共4页
张凡凡%王莹莹%杨莉%杨金生
張凡凡%王瑩瑩%楊莉%楊金生
장범범%왕형형%양리%양금생
肿瘤%白细胞减少%中药%用药规律
腫瘤%白細胞減少%中藥%用藥規律
종류%백세포감소%중약%용약규률
Cancer%Leukopenia%Chinese medicine%Medication Rule
目的：对近10年治疗肿瘤放化疗后白细胞减少的用药进行回顾性分析，为临床选方用药提供依据和思路。方法：收集整理2004—2013年中国期刊全文数据库、中国生物医学文献数据库、万方数据库收录的有关中医或中西医结合治疗肿瘤放化疗后白细胞减少的方药记载文献。参照《中华人民共和国药典》和《中药学》的专业术语为标准，应用 SPSS 13．0统计学软件对文献资料的单味药频次、药物功效、中药性味归经进行分类统计。结果：检索到相关文献103篇，涉及114首复方、148味中药、18类药。单味药使用总频次是1229次，以补虚药（66．4％）、活血化瘀药（7．16％）、消食药（5．04％）为主，其中黄芪使用频次最多，为91次，占79．8％；药性以温、平、寒药为主，温性药占52．5％；药味多为甘、苦、辛，甘味药占52．7％；药物归经以脾经、肝经、肾经为主。结论：肿瘤放化疗后白细胞减少的治疗原则多以扶正为本，重在补益气血，调理脾、肝、肾，黄芪为常用治疗药物，基本贯穿于治疗始末。
目的：對近10年治療腫瘤放化療後白細胞減少的用藥進行迴顧性分析，為臨床選方用藥提供依據和思路。方法：收集整理2004—2013年中國期刊全文數據庫、中國生物醫學文獻數據庫、萬方數據庫收錄的有關中醫或中西醫結閤治療腫瘤放化療後白細胞減少的方藥記載文獻。參照《中華人民共和國藥典》和《中藥學》的專業術語為標準，應用 SPSS 13．0統計學軟件對文獻資料的單味藥頻次、藥物功效、中藥性味歸經進行分類統計。結果：檢索到相關文獻103篇，涉及114首複方、148味中藥、18類藥。單味藥使用總頻次是1229次，以補虛藥（66．4％）、活血化瘀藥（7．16％）、消食藥（5．04％）為主，其中黃芪使用頻次最多，為91次，佔79．8％；藥性以溫、平、寒藥為主，溫性藥佔52．5％；藥味多為甘、苦、辛，甘味藥佔52．7％；藥物歸經以脾經、肝經、腎經為主。結論：腫瘤放化療後白細胞減少的治療原則多以扶正為本，重在補益氣血，調理脾、肝、腎，黃芪為常用治療藥物，基本貫穿于治療始末。
목적：대근10년치료종류방화료후백세포감소적용약진행회고성분석，위림상선방용약제공의거화사로。방법：수집정리2004—2013년중국기간전문수거고、중국생물의학문헌수거고、만방수거고수록적유관중의혹중서의결합치료종류방화료후백세포감소적방약기재문헌。삼조《중화인민공화국약전》화《중약학》적전업술어위표준，응용 SPSS 13．0통계학연건대문헌자료적단미약빈차、약물공효、중약성미귀경진행분류통계。결과：검색도상관문헌103편，섭급114수복방、148미중약、18류약。단미약사용총빈차시1229차，이보허약（66．4％）、활혈화어약（7．16％）、소식약（5．04％）위주，기중황기사용빈차최다，위91차，점79．8％；약성이온、평、한약위주，온성약점52．5％；약미다위감、고、신，감미약점52．7％；약물귀경이비경、간경、신경위주。결론：종류방화료후백세포감소적치료원칙다이부정위본，중재보익기혈，조리비、간、신，황기위상용치료약물，기본관천우치료시말。
Objective:To analyze retrospectively the medications for leukopenia after radio-chemotherapy in cancer treated in re-cent decade years so as to provide the evidence and approaches to the application of Chinese medicine in clinic.Methods:The lit-eratures on Chinese medicine formulas were collected from Chinese Journal Full-text Database and Chinese Biological Medicine on Disc and Wanfang Database in terms of the treatment of leukopenia after radio-chemotherapy in cancer with traditional Chinese medicine or integrated Chinese and western medicine from year 2004 to 201 3.In reference to the standard terminology in Pharma-copoeia of the People’s Republic of Chinese and Chinese Materia mMdica,using SPSS1 3.0 statistical software,the usage frequency of single herb,drug efficacy and nature,flavor and channel tropism of Chinese herbs were classified and analyzed statistically.Re-sults:One hundred and three relevant literatures were retrieved,among which,there were 1 1 4 Chinese herbal formulas,1 48 differ-ent herbs and 1 8 categories of Chinese herbal medicine.The total frequency of single herb was 1 229 times.Among those different herbs,66.4% of them were in the category of replenishing the deficiency,7.1 6% of them were of activating blood circulation and resolving stasis and 5.04% of them were of promoting digestion.Astragalus membranaceus was on the top in usage frequency,to-tally 91 times,accounting for 79.8%.Regarding the nature of Chinese herbal medicine,the warm,neutral and cold natures were predominated,in which,those of warm nature accounted for 52.5%.Regarding to the flavor,sweet,bitter and pungent flavors were predominated,in which,those of sweet flavor accounted for 52.7%.Regarding to channel tropism,spleen,liver and kidney channels were mainly involved.Conclusion:In the treatment of leukopenia after radio-chemotherapy in cancer,strengthening the antipathogenic qi is the root,also it requires focusing on tonifying qi and blood,and regulating the functions of spleen,liver and kidney.Astragalus membranaceus is the common herb in the entire process of treatment.
