CAJ | 학술논문

目的：观察椎旁神经阻滞复合臭氧治疗腰椎间盘突出的远期临床疗效。方法90例经临床诊断证实为腰椎间盘突出合并椎管狭窄症患者随机分为两组：A组（n=45）单纯经椎旁间隙穿刺成功后注入消炎镇痛药20 ml；B组（n=45）经椎旁间隙穿刺成功后注入消炎镇痛药20 ml+40μg/ml臭氧10 ml；每周一次，3~4次为一疗程。对病人治疗后1个月、6个月的疗效进行随访观察，项目包括：①临床疼痛评价：采用疼痛视觉模拟评分法（ VAS）进行评估；②治疗有效率：采用改良的MacNab法评价疗效。结果①VAS疼痛评分：两组组内比较，A组治疗后6个月的疼痛评分高于1个月的评分数值，差异有统计学意义（ P <0.05）。组间比较，B组治疗后6个月临床疗效稳定性高于A组，差异有统计学意义（ P <0.05）。②治疗总有效率：两组组内比较，A组治疗后6个月的治疗总有效率低于1个月的评分数值，差异有统计学意义（ P <0.05）。组间比较显示，B组治疗后6个月治疗总有效率高于A组，差异有统计学意义（ P <0.05）。结论椎旁神经阻滞复合臭氧治疗腰椎间盘突出的远期临床稳定性效果明显。
목적：관찰추방신경조체복합취양치료요추간반돌출적원기림상료효。방법90례경림상진단증실위요추간반돌출합병추관협착증환자수궤분위량조：A조（n=45）단순경추방간극천자성공후주입소염진통약20 ml；B조（n=45）경추방간극천자성공후주입소염진통약20 ml+40μg/ml취양10 ml；매주일차，3~4차위일료정。대병인치료후1개월、6개월적료효진행수방관찰，항목포괄：①림상동통평개：채용동통시각모의평분법（ VAS）진행평고；②치료유효솔：채용개량적MacNab법평개료효。결과①VAS동통평분：량조조내비교，A조치료후6개월적동통평분고우1개월적평분수치，차이유통계학의의（ P <0.05）。조간비교，B조치료후6개월림상료효은정성고우A조，차이유통계학의의（ P <0.05）。②치료총유효솔：량조조내비교，A조치료후6개월적치료총유효솔저우1개월적평분수치，차이유통계학의의（ P <0.05）。조간비교현시，B조치료후6개월치료총유효솔고우A조，차이유통계학의의（ P <0.05）。결론추방신경조체복합취양치료요추간반돌출적원기림상은정성효과명현。
Objective To observe the long-term clinical effect of paravertebral block combined with ozone in patients with lumber disc herniation. Methods Ninety patients with lumber disc herniation accompanied by lumber spinal canal stenosis confirmed by clinical diagnosis were randomly divided into group A(n=45)in which a volume of 20ml analgesic and anti-inflammatory drugs was injected to perform paraverte-bral block and group B(n=45)in which a volume of 20 ml analgesic and anti-inflammatory drugs combined with a volume of 10 ml(40 μg/ml)ozone was injected to perform paravertebral block. There was one paravertebral block in a week and three or four paravertebral blocks in a treatment course. The clinical effect including visual analogue scale( VAS)and treatment efficiency at 1 month and 6 months after the treatment were observed. Results The VAS at 6 month after the treatment was significantly higher than that at 1 month after the treatment in group A( P<0. 05)and there was no such a significant difference in group B. The total treatment efficiency at 6 months after the treatment in group B was significantly higher than that in group A( P <0. 05). Conclusion The long-term clinical effect of paravertebral block combined with ozone in patients with lumber disc herniation is definite and stable.