CAJ | 학술논문

目的：基于数据挖掘技术探讨难治性尿路感染相关文献及医案的中医辨治用药规律。方法：在中国知网数据库中检索、下载难治性尿路感染相关文献，通过筛选、清洗、降噪处理及目标关键词频数统计的数据分层算法，挖掘难治性尿路感染的病因、病位、病机、主症、舌脉、证型、治法、方剂、中药规律，并进行可视化展示。结果：该病的病因、病机主要涉及正虚、邪实两端，证型以肾虚、膀胱湿热为主；治法以清热利湿兼补肾养阴为主；涉及的方药主要为补肾、清利类。结论：该研究应用数据挖掘技术对文献全文、病案处方进行系统、细致、分层次的总结。理、法、方、药诸层次的研究结果与临床实践对该病的认识有较好的一致性。
목적：기우수거알굴기술탐토난치성뇨로감염상관문헌급의안적중의변치용약규률。방법：재중국지망수거고중검색、하재난치성뇨로감염상관문헌，통과사선、청세、강조처리급목표관건사빈수통계적수거분층산법，알굴난치성뇨로감염적병인、병위、병궤、주증、설맥、증형、치법、방제、중약규률，병진행가시화전시。결과：해병적병인、병궤주요섭급정허、사실량단，증형이신허、방광습열위주；치법이청열리습겸보신양음위주；섭급적방약주요위보신、청리류。결론：해연구응용수거알굴기술대문헌전문、병안처방진행계통、세치、분층차적총결。리、법、방、약제층차적연구결과여림상실천대해병적인식유교호적일치성。
Objective:To explore the traditional treatment rules of refractory urinary tract infections through data mining.Meth-ods:We collected as much literature on refractory urinary tract infections as we can via China Knowledge Resource Integrated Da-tabase (KNS).Through noise suppression and data slicing algorithm based on sensitive keywords frequency,we summarized the disease’etiology,pathogenesis,site of infection,tongue manifestation,symptom,syndrome,treatment methods,TCM formula, visualize the treatment rule in one dimensional level and in two-dimensional network diagram.Results:The TCMetiology and path-ogenesis of refractory urinary tract infections concerns vital qi deficiency when pathogenic qi is prevailing.Kidney deficiency and bladder damp-heat was the main pathogenesis.Treatment methods include tonifying kidney,cleaning heat and dispelling damp. The results is well consistent with our clinical practice.Conclusion:With data mining,we systematically reviewed the literatures and prescriptions of refractory urinary tract infections and make objective summary of the rules of treatment.