CAJ | 학술논문

目的：观察盐酸曲马多缓释片联合普瑞巴林治疗卒中后丘脑痛的临床疗效，并为临床治疗提供参考。方法选取2010年7月至2014年12月解放军总医院疼痛科收治的脑卒中后丘脑痛患者40例，分为两组，试验组22例给予曲马多联合普瑞巴林治疗，对照组18例单独给予曲马多治疗。结果试验组治疗后疼痛程度[数字等级评分量表（NRS）评分]明显降低，且降低效果相比对照组更为显著，其临床治疗显效率及总有效率明显高于对照组（ P＜0.05）。结论使用曲马多联合普瑞巴林胶治疗脑卒中后丘脑痛，能有效缓解其疼痛程度，并能改善躯体的不适，相比单纯使用曲马多治疗具有更为理想的临床疗效，不良反应较少，值得临床推广。
목적：관찰염산곡마다완석편연합보서파림치료졸중후구뇌통적림상료효，병위림상치료제공삼고。방법선취2010년7월지2014년12월해방군총의원동통과수치적뇌졸중후구뇌통환자40례，분위량조，시험조22례급여곡마다연합보서파림치료，대조조18례단독급여곡마다치료。결과시험조치료후동통정도[수자등급평분량표（NRS）평분]명현강저，차강저효과상비대조조경위현저，기림상치료현효솔급총유효솔명현고우대조조（ P＜0.05）。결론사용곡마다연합보서파림효치료뇌졸중후구뇌통，능유효완해기동통정도，병능개선구체적불괄，상비단순사용곡마다치료구유경위이상적림상료효，불량반응교소，치득림상추엄。
ObjectiveTodetermine the clinical efficacy of sustained release tablets of hydrochloride tramadol combined with pregabalin on the treatment of post-stroke thalamic pain in order to provide reference for clinical practice.Methods Forty patients with post-stroke thalamic painadmitted into our department from July 2010 to December 2014 were randomly divided into 2 groups,test group (tramadol and pregabalin,n=22) and control group (tramadol alone,n=18).Results NumericalRatingScale (NRS)indicated that the pain level was significantly relieved in thetest group after the treatment, and the relief was more significant than that of the control group. The effective rate and total effective rate of clinical treatment were significantly higherin thetest group thaninthe control group (P<0.05).Conclusion Combination of tramadol and pregabalin can effectivelyrelievethe post-stroke thalamic pain andattenuate physical discomfort. Superior tosimple tramadol, the treatment is ofmore ideal clinical efficacy and fewer adverse effects, andisworthy of clinical promotion.