CAJ | 학술논문

目的：探讨新辅助化疗结合保肢手术治疗骨肉瘤临床效果。方法：选取2010年5月-2013年5月47例采用新辅助化疗结合保肢手术治疗的骨肉瘤患者为观察组，同期仅实施保肢手术治疗的骨肉瘤患者47例作为对照组，观察比较两组患者治疗后临床效果。结果：观察组患者临床疗效明显高于对照组，组间差异有统计学意义（ P＜0.05）；两组优良率及总有效率比较，观察组均明显优于对照组，组间比较差异有统计学意义（P＜0.05）；治疗后6个月、1年、3年时间随访两组患者的复发、转移、死亡率，对照组均明显高于观察组，差异有统计学意义（ P＜0.05）。结论：新辅助化疗结合保肢手术治疗骨肉瘤近远期临床效果显著。
목적：탐토신보조화료결합보지수술치료골육류림상효과。방법：선취2010년5월-2013년5월47례채용신보조화료결합보지수술치료적골육류환자위관찰조，동기부실시보지수술치료적골육류환자47례작위대조조，관찰비교량조환자치료후림상효과。결과：관찰조환자림상료효명현고우대조조，조간차이유통계학의의（ P＜0.05）；량조우량솔급총유효솔비교，관찰조균명현우우대조조，조간비교차이유통계학의의（P＜0.05）；치료후6개월、1년、3년시간수방량조환자적복발、전이、사망솔，대조조균명현고우관찰조，차이유통계학의의（ P＜0.05）。결론：신보조화료결합보지수술치료골육류근원기림상효과현저。
Objective:To investigate clinical effect of neoadjuvant chemotheraPy combined with limb salvage sur-gery for osteosarcoma. Methods:All 47 osteosarcoma Patients were treated by chemotheraPy combined with limb sal-vage surgery in the observation grouP,47 Patients limb salvage surgery as the control grouP. Results:The clinical effi-cacy was significantly higher in observe grouP Patients(P<0. 05). After 6 months,1 year,3 years of follow-uP re-laPse,metastasis,mortality was significantly higher than the control grouP( P <0. 05 ). Conclusion:Neoadjuvant chemotheraPy combined with limb salvage surgery for osteosarcoma short and long term clinical results are effective.