现代肿瘤医学
現代腫瘤醫學
현대종류의학
JOURNAL OF MODERN ONCOLOGY
2015年
13期
1902-1904,1905
,共4页
朱美琴%申维玺%夏俊贤%田忠凯%陈亦欣%叶建增
硃美琴%申維璽%夏俊賢%田忠凱%陳亦訢%葉建增
주미금%신유새%하준현%전충개%진역흔%협건증
晚期恶性肿瘤%血清肿瘤相关物质%检测
晚期噁性腫瘤%血清腫瘤相關物質%檢測
만기악성종류%혈청종류상관물질%검측
advanced malignant tumor%Bo xin serum tumor associated material%detection
目的：探讨晚期恶性肿瘤患者血清肿瘤相关物质（ BXTM）含量检测及临床价值。方法：检测250例有复发转移的晚期恶性肿瘤患者、60例无复发转移患者和60例健康体检者血清BXTM含量。结果：晚期恶性肿瘤组BXTM均值为（112.10±20.20）U/ml，阳性率为72.8%。无复发转移患者BXTM均值为（92.35±12.25）U/ml，阳性率为25.0%。正常对照者BXTM均值为（91.28±9.35）U/ml，阳性率为16.7%。复发转移患者血清BXTM含量明显高于无复发转移患者及正常对照者（ P＜0.05）。无复发转移患者和正常对照者血清BXTM含量无差异（ P＞0.05）。治疗有效或稳定的患者化疗前血清 BXTM 含量及其阳性率均低于疾病进展的患者（ P＜0.05）。结论：血清BXTM检测具有较高的敏感性、特异性和广谱性，临床上可用作晚期恶性肿瘤诊断、疗效判断以及随访检测的参考指标。
目的：探討晚期噁性腫瘤患者血清腫瘤相關物質（ BXTM）含量檢測及臨床價值。方法：檢測250例有複髮轉移的晚期噁性腫瘤患者、60例無複髮轉移患者和60例健康體檢者血清BXTM含量。結果：晚期噁性腫瘤組BXTM均值為（112.10±20.20）U/ml，暘性率為72.8%。無複髮轉移患者BXTM均值為（92.35±12.25）U/ml，暘性率為25.0%。正常對照者BXTM均值為（91.28±9.35）U/ml，暘性率為16.7%。複髮轉移患者血清BXTM含量明顯高于無複髮轉移患者及正常對照者（ P＜0.05）。無複髮轉移患者和正常對照者血清BXTM含量無差異（ P＞0.05）。治療有效或穩定的患者化療前血清 BXTM 含量及其暘性率均低于疾病進展的患者（ P＜0.05）。結論：血清BXTM檢測具有較高的敏感性、特異性和廣譜性，臨床上可用作晚期噁性腫瘤診斷、療效判斷以及隨訪檢測的參攷指標。
목적：탐토만기악성종류환자혈청종류상관물질（ BXTM）함량검측급림상개치。방법：검측250례유복발전이적만기악성종류환자、60례무복발전이환자화60례건강체검자혈청BXTM함량。결과：만기악성종류조BXTM균치위（112.10±20.20）U/ml，양성솔위72.8%。무복발전이환자BXTM균치위（92.35±12.25）U/ml，양성솔위25.0%。정상대조자BXTM균치위（91.28±9.35）U/ml，양성솔위16.7%。복발전이환자혈청BXTM함량명현고우무복발전이환자급정상대조자（ P＜0.05）。무복발전이환자화정상대조자혈청BXTM함량무차이（ P＞0.05）。치료유효혹은정적환자화료전혈청 BXTM 함량급기양성솔균저우질병진전적환자（ P＜0.05）。결론：혈청BXTM검측구유교고적민감성、특이성화엄보성，림상상가용작만기악성종류진단、료효판단이급수방검측적삼고지표。
Objective:To investigate the value of the Bo xin serum tumor associated material( BXTM)in the diag-nosis of advanced malignant tumors. Methods:With the method of chemical colorimetry,the level of BXTM was deter-mined and comPared in 250 cases with advanced malignant tumor,60 cases with early malignant tumor and 60 Physi-cal examination volunteers. Results:The mean value of BXTM in advanced malignant tumor Patients was(112. 10 ± 20. 20)U/ml,and the sensitive rate was 72. 8%. The mean value of BXTM in early malignant tumor Patients was (92. 35 ± 12. 25)U/ml,and the sensitive rate was 25. 0%. The mean value of BXTM in normal PeoPle was(91. 28 ± 9. 35)U/ml,and the sensitive rate was 16. 7%. The levels of BXTM in serum of advanced malignant tumor Patients were significantly higher than those of early malignant tumor Patients and normal PeoPle(P<0. 05). The levels of BXTM in serum of early malignant tumor Patients and normal PeoPle had no difference(P >0. 05). The levels of BXTM in Patients that achieved PR or SD were less than that had PD(P<0. 05). Conclusion:Detecting BXTM in advanced malignant tumor Patients has a higher sensitivity,sPecificity,and wide sPectrum. It can be used as the indi-cator for the diagnosis,treatment effect and follow uP in advanced malignant tumors.
