现代肿瘤医学
現代腫瘤醫學
현대종류의학
JOURNAL OF MODERN ONCOLOGY
2015年
13期
1900-1902
,共3页
奥曲肽%放射治疗%急性腹泻%疗效
奧麯肽%放射治療%急性腹瀉%療效
오곡태%방사치료%급성복사%료효
octreotide%radiotheraPy%acute diarrhea%theraPeutic efficacy
目的：观察奥曲肽治疗放疗相关性腹泻的疗效。方法：2011年8月-2014年9月我院收治在放疗过程中出现Ⅱ-Ⅳ级腹泻的患者67例，Ⅱ-Ⅲ级患者应用奥曲肽100μg皮下注射，每天3次，Ⅳ级患者给予奥曲肽25μg/h，持续泵入，每天8-12h，观察腹泻的治疗效果。结果：奥曲肽治疗67例放疗相关性腹泻的治愈率为85.07%，治疗后患者Karnofsky体力状态（ KPS）评分明显提高，未见明显不良反应。结论：奥曲肽治疗放疗相关性腹泻，尤其对Ⅱ-Ⅲ级腹泻有较好的疗效，安全可靠，有效改善患者生存治疗，保障放疗顺利进行。
目的：觀察奧麯肽治療放療相關性腹瀉的療效。方法：2011年8月-2014年9月我院收治在放療過程中齣現Ⅱ-Ⅳ級腹瀉的患者67例，Ⅱ-Ⅲ級患者應用奧麯肽100μg皮下註射，每天3次，Ⅳ級患者給予奧麯肽25μg/h，持續泵入，每天8-12h，觀察腹瀉的治療效果。結果：奧麯肽治療67例放療相關性腹瀉的治愈率為85.07%，治療後患者Karnofsky體力狀態（ KPS）評分明顯提高，未見明顯不良反應。結論：奧麯肽治療放療相關性腹瀉，尤其對Ⅱ-Ⅲ級腹瀉有較好的療效，安全可靠，有效改善患者生存治療，保障放療順利進行。
목적：관찰오곡태치료방료상관성복사적료효。방법：2011년8월-2014년9월아원수치재방료과정중출현Ⅱ-Ⅳ급복사적환자67례，Ⅱ-Ⅲ급환자응용오곡태100μg피하주사，매천3차，Ⅳ급환자급여오곡태25μg/h，지속빙입，매천8-12h，관찰복사적치료효과。결과：오곡태치료67례방료상관성복사적치유솔위85.07%，치료후환자Karnofsky체력상태（ KPS）평분명현제고，미견명현불량반응。결론：오곡태치료방료상관성복사，우기대Ⅱ-Ⅲ급복사유교호적료효，안전가고，유효개선환자생존치료，보장방료순리진행。
Objective:To exPlore the efficacy of octreotide in the treatment of radiotheraPy-induced acute diar-rhea( RID). Methods:All 67 Patients with grade Ⅱ-Ⅳ diarrhea during celiac or Pelvic radiotheraPy were analyzed during August 2011 and SePtember 2014. The grade Ⅱ-Ⅲ Patients were given the subcutaneous injection of oct-reotide(100μg,tid). The grade Ⅳ Patients were continuously infused with 25μg/h octreotide for 8 -12h/day. Re-sults:The overall resPonse rate was 85. 07%. After treatment,the KPS scores were significantly imProved. In addition, no obvious adverse reaction was found. Conclusion:The theraPeutic efficacy of octreotide in the treatment of RID was effective and safe,and dramatically imProved the quality of life of Patients.
