中西医结合心脑血管病杂志
中西醫結閤心腦血管病雜誌
중서의결합심뇌혈관병잡지
CHINESE JOURNAL OF INTEGRATIVE MEDICINE ON CARDIO-/CEREBROVASCULAR DISEASE
2015年
6期
725-727
,共3页
急性心肌梗死%认知功能障碍%影响因素
急性心肌梗死%認知功能障礙%影響因素
급성심기경사%인지공능장애%영향인소
acute myocardial infarction%cognitive dysfunction%risk factor
目的：研究急性心肌梗死患者发生认知功能障碍的影响因素。方法选择2010年2月—2014年1月航空总医院心血管内科收治的420例急性心肌梗死患者，收集患者一般临床资料并应用蒙特利尔认知评估量表(MoCA)评估患者认知功能及焦虑抑郁状态，采用多因素Logistic回归方法分析认知功能障碍的危险因素。结果认知功能障碍组和对照组在吸烟、年龄、空腹血糖受损、心房颤动、糖耐量受损、糖尿病、高密度脂蛋白胆固醇(HDL C)、收缩压及焦虑抑郁方面差异有统计学意义(P<0.05)，行多因素Logistic回归分析，年龄、心房颤动、收缩压、糖尿病、HDL C及焦虑抑郁是急性心肌梗死患者发生认知功能障碍的独立危险因素(P<0.05)。广泛前壁和右室梗死与急性心肌梗死患者认知功能障碍密切相关(P<0.05)。结论急性心肌梗死患者发生认知功能障碍较高，对于重要部位梗死及合并心房颤动、高血压病、糖尿病的患者更应加强关注，重视其心理疏导和治疗，缓解抑郁状态，有助于对认知功能障碍早发现、早干预。
目的：研究急性心肌梗死患者髮生認知功能障礙的影響因素。方法選擇2010年2月—2014年1月航空總醫院心血管內科收治的420例急性心肌梗死患者，收集患者一般臨床資料併應用矇特利爾認知評估量錶(MoCA)評估患者認知功能及焦慮抑鬱狀態，採用多因素Logistic迴歸方法分析認知功能障礙的危險因素。結果認知功能障礙組和對照組在吸煙、年齡、空腹血糖受損、心房顫動、糖耐量受損、糖尿病、高密度脂蛋白膽固醇(HDL C)、收縮壓及焦慮抑鬱方麵差異有統計學意義(P<0.05)，行多因素Logistic迴歸分析，年齡、心房顫動、收縮壓、糖尿病、HDL C及焦慮抑鬱是急性心肌梗死患者髮生認知功能障礙的獨立危險因素(P<0.05)。廣汎前壁和右室梗死與急性心肌梗死患者認知功能障礙密切相關(P<0.05)。結論急性心肌梗死患者髮生認知功能障礙較高，對于重要部位梗死及閤併心房顫動、高血壓病、糖尿病的患者更應加彊關註，重視其心理疏導和治療，緩解抑鬱狀態，有助于對認知功能障礙早髮現、早榦預。
목적：연구급성심기경사환자발생인지공능장애적영향인소。방법선택2010년2월—2014년1월항공총의원심혈관내과수치적420례급성심기경사환자，수집환자일반림상자료병응용몽특리이인지평고량표(MoCA)평고환자인지공능급초필억욱상태，채용다인소Logistic회귀방법분석인지공능장애적위험인소。결과인지공능장애조화대조조재흡연、년령、공복혈당수손、심방전동、당내량수손、당뇨병、고밀도지단백담고순(HDL C)、수축압급초필억욱방면차이유통계학의의(P<0.05)，행다인소Logistic회귀분석，년령、심방전동、수축압、당뇨병、HDL C급초필억욱시급성심기경사환자발생인지공능장애적독립위험인소(P<0.05)。엄범전벽화우실경사여급성심기경사환자인지공능장애밀절상관(P<0.05)。결론급성심기경사환자발생인지공능장애교고，대우중요부위경사급합병심방전동、고혈압병、당뇨병적환자경응가강관주，중시기심리소도화치료，완해억욱상태，유조우대인지공능장애조발현、조간예。
Objective To study the influencing factors of cognitive dysfunction in patients with acute myocardial infarction(AMI).Meth-ods Four hundreds and twenty patients with AMI were selected from February 2010 to January 2014 in Department of cardiovascu-lar medicine in Aviation General Hospital.The clinical data were col ected.The cognitive function in patients with depression was as-sessed by the Montreal Cognitive Assessment(MoCA).The risk factors of cognitive dysfunction were analysed by multivariate Logistic regression method.Results There was significant difference in age,smoking,atrial fibril ation,anemia,impaired fasting glucose,im-paired glucose tolerance,diabetes,systolic blood pressure between the cognitive dysfunction group and cognitive control group(P<0.05).The multivariate Logistic regression analysis showed that age,atrial fibril ation,diabetes,systolic blood pressure,HDL C and depression were independent risk factors of cognitive dysfunction in patients with AMI(P<0.05).Extensive anteriord and right ven-tricular infarction in patients with cognitive dysfunction was closely related (P<0.05).Conclusion The patients with AMI had a high-er incidence of cognitive dysfunction.Patients with the key parts infarction or complicated with atrial fibril ation,hypertension,iabetes should strengthen attention.We should emphasis on the psychological counseling and treatment,al eviate depression,and contribute to the early detection and intervention of cognitive dysfunction.
