CAJ | 학술논문

目的：探讨失代偿期肝硬化的治疗效果。方法：随机抽取2012年1月-2014年12月笔者所在医院收治的78例失代偿期肝硬化患者作为观察对象，并对其临床资料进行回顾性分析，所有患者均实施保肝、抗病毒及降转氨酶、退黄等常规性治疗，合并腹水患者则口服利尿剂，对钠盐摄入量进行严格控制。同时应用还原型谷胱苷肽1500 mg静脉滴注，4周后评价治疗效果。结果：通过积极合理治疗干预后，78例患者，显效54例，有效18例，无效6例，总有效率为92.3%。治疗后ALT、AST、TBIL、ALB、A/G等肝功能指标改善明显，与治疗前相比差异均有统计学意义(P<0.05)。结论：对失代偿期肝硬化患者采取综合性治疗，能够显著提高临床诊疗效果，并发挥护肝、降转氨酶、抗纤维化、抗肝硬化作用。
목적：탐토실대상기간경화적치료효과。방법：수궤추취2012년1월-2014년12월필자소재의원수치적78례실대상기간경화환자작위관찰대상，병대기림상자료진행회고성분석，소유환자균실시보간、항병독급강전안매、퇴황등상규성치료，합병복수환자칙구복이뇨제，대납염섭입량진행엄격공제。동시응용환원형곡광감태1500 mg정맥적주，4주후평개치료효과。결과：통과적겁합리치료간예후，78례환자，현효54례，유효18례，무효6례，총유효솔위92.3%。치료후ALT、AST、TBIL、ALB、A/G등간공능지표개선명현，여치료전상비차이균유통계학의의(P<0.05)。결론：대실대상기간경화환자채취종합성치료，능구현저제고림상진료효과，병발휘호간、강전안매、항섬유화、항간경화작용。
Objective:To investigate the therapeutic effect of decompensated cirrhosis.Method:78 patients with decompensated cirrhosis were randomly selected in our hospital from January 2012 to December 2014 as the research objects,and the clinical data were analyzed retrospectively.All patients were liver and lowering transaminase implementation,antiviral,jaundice and other conventional treatment.Patients with ascites were oral diuretics,strict control of sodium intake.At the same time the application of glutathione intravenous infusion of 1500 mg,evaluated the therapeutic effect after 4 weeks.Result:After the intervention through active therapy,all patients,excellent in 54 cases,effective in 18 cases,ineffective in 6 cases,the total efficiency rata was 92.3%.ALT,AST,TBIL, ALB,A/G and other indexes of liver function were improved significantly in patients after treatment,compared with before treatment(P<0.05).Conclusion:The decompensation liver cirrhosis patients with comprehensive treatment,can significantly improve the clinical effect,and it plays a role of anti liver cirrhosis liver, reducing aminotransferase,anti fibrosis.